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In response to various environmental stresses including heavy metals, the c-Jun N-terminal kinase (JNK) is phosphorylated and then it phosphorylates c-Jun protein. In the present study, effects of mercury chloride (HgCl2) on JNK signalling pathway were examined in LLC-PK1 cells. When exposed to 10 or 20 microM HgCl2, the level of phosphorylated JNK and the activity of JNK assayed in vitro using...

Zinc chloride protected against lethality in mice undergoing endotoxin shock.

Doping of zinc with silver, palladium, and gold was found to increase reactivity towards carbon tetrachloride in water. Commercial zinc dust, cryochemically prepared zinc metal particles (SMAD nanoparticles), and zinc dust pressed into pellets (mechanically activated zinc) were employed. Reduction products detected were methane, ethylene, acetylene, and other hydrocarbons along with products of...

BACKGROUND Despite all progresses in surgical science, bleeding caused by traffic accidents is still a challenge for surgeons to save patients' lives. Therefore, introducing an effective method to control external bleeding is an important research priority. OBJECTIVES This study aimed to compare haemostatic effect of zinc chloride and simple suturing to control external bleeding. MATERIALS ...

We recently reported a phenotypic association between reduced susceptibility to zinc and methicillin resistance in Staphylococcus aureus CC398 isolates from Danish swine (F. M. Aarestrup, L. M. Cavaco, and H. Hasman, Vet. Microbiol. 142:455-457, 2009). The aim of this study was to identify the genetic determinant causing zinc resistance in CC398 and examine its prevalence in isolates of animal ...

Zinc has been shown to have antioxidant properties and to exhibit inhibitory effects on apoptosis. In this work we investigated the effect of zinc on DNA integrity and on apoptosis of HaCaT keratinocytes. Cells were submitted to zinc deprivation by a diffusible zinc chelator, (N,N,N',N'-tetrakis (2-pyridylmethyl)ethylenediamine) (TPEN) or supplied with zinc chloride and submitted to UVB radiati...

This work is a preliminary examination of mechanistic issues on the comparative corrosion performance of regular epoxy-coated rebar (ECR) and dual polymer-zinc coated reinforcement (DCR) in simulated concrete pore solution with and without chloride ions, at polarizations from +100 mV to -1000 mV in the saturated calomel electrode (SCE) scale and exposure periods of 1 month or longer. Both mater...

Galvanic corrosion protection by embedded zinc anodes is an accepted technique for the of reinforcing steel in concrete. currents flow between anode and reinforcement due to potential difference that range a few hundred mV. The ion distribution was studied on two reinforced concrete specimens admixed with 3 wt.% chloride/wt. cement galvanically protected surface applied EZ-anode. On both specim...