The E2A gene encodes two alternatively spliced products, E12 and E47. The two proteins differ in their basic helix-loop-helix motifs (bHLH), responsible for DNA binding and dimerization. Although both E12 and E47 can bind to DNA as heterodimers with tissue-specific bHLH proteins, E12 binds to DNA poorly as homodimers. An inhibitory domain in E12 has previously been found to prevent E12 homodime...

This survey discusses behavioral and experimental macroeconomics, emphasizing a complex systems perspective. The economy consists of boundedly rational heterogeneous agents who do not fully understand their environment use simple decision heuristics. Central to our is the question under which conditions macro-system interacting may or coordinate on equilibrium outcome. A general finding that po...

Abstract Wineries in the “old world” export almost 40% of their production. This study analyzes influence vertical and horizontal networks on performance. We draw a sample 183 Spanish wineries examine main independent variables using two-step Heckman model. find positive effects and—at somewhat lower level—downstream (JEL Classifications: L66, M16, Q13)

We study supply and demand shocks in a disaggregated model with multiple sectors, factors, input-output linkages, downward nominal wage rigidities, credit-constraints, zero lower bound. use the to understand how COVID-19 crisis, an omnibus shock, affects output, unemployment, inflation, leads coexistence of tight slack labor markets. show that negative sectoral are stagflationary, whereas defla...

In a previous essay, we developed a simple (in)efficiency measure for matrix games. We now address the difficulties encountered in assessing the usefulness and accuracy of such a measure. JEL Classifications: C63, C72, D61

We show that for any mechanism there exists an equivalent dominant strategy incentive compatible mechanism for social choice environments with correlated types when agent’s matrix of conditional probabilities satisfies the full rank condition. JEL classifications: D82

An overview is given of the utilization of strategic market games in the development of a game theory based theory of money and financial institutions. JEL Classifications: C72, C73, E44

the aim of this paper is to investigate the existence of the new non-ricardian regime policy in iranian economy. we detected signs of the non-ricardian regime from quarterly data of 1369 to 1391. to investigate further a dynamic stochastic general equilibrium model is designed to estimate the fiscal and monetary parameters using a bayesian approach. our results indicated a passive monetary poli...

It is common to note that social environment and cultural formation shape mental disorders. The details of this claim are, however, not well understood. The paper takes a look at the claim that culture has an impact on psychiatry from the perspective of metaphysics and the philosophy of science. Its aim is to offer, in a general fashion, partial explications of some significant versions of the ...

Phenotypic transformation of mesangial cells (MCs) is implicated in the development of glomerular disease; however, the mechanisms underlying their altered genetic program is still unclear. α-smooth muscle actin (α-SMA) is known to be a crucial marker for phenotypic transformation of MCs. Recently, E-boxes and the class I basic helix-loop-helix proteins, such as E12 have been shown to regulateα...