This study sought to investigate the cardiac and renal effects of rigorous versus standard BP control on autosomal-dominant polycystic kidney disease (ADPKD). A prospective, randomized, 7-yr study was performed to examine the effect of rigorous (<120/80 mmHg) versus standard (135-140/85-90 mmHg) BP control on left ventricular mass index (LVMI) and kidney function in 75 hypertensive ADPKD patien...

BACKGROUND AND OBJECTIVES Heart disease is a major cause of death in young adults with chronic kidney disease (CKD). Left ventricular hypertrophy (LVH) is common and is associated with hypertension. The aims of this study were to evaluate whether there is a relationship between LVH and BP in children with CKD and whether current targets for BP control are appropriate. DESIGN, SETTING, PARTICI...

OBJECTIVE To asses the values of echocardiographic measurements in normal children without cardiopathy and to build percentile curves, relating them to the body surface (BS, m(2)). METHODS We analyzed M-mode echocardiographic measurements for children between one and 144 months of age. We assessed right ventricular diastolic diameter (RVDd, mm) and left ventricular diastolic diameter (LVDd, m...

Background: A prospective study was conducted to find distribution of the left ventricular mass in normal adult Nepalese population order establish upper reference limit.&#x0D; Materials and Methods: total 100 consecutive male female participants age 18 years above visiting for cardiac checkup were enrolled prospectively this study. Participants with hypertension, diabetes, obesity significant ...

Asymmetric dimethylarginine (ADMA) has been involved in the development mechanism of cardiovascular disease (CVD) in patients with chronic kidney disease. The aim of this study is to investigate the relationship between the plasma ADMA levels and echocardiography, and understand the relationship between ADMA and left ventricular function. All of the patients were divided into three groups, incl...

AIM To investigate the association between hepatic steatosis and change in left ventricular mass index (LVMI) over five years, and examine whether systolic and diastolic blood pressures are mediators of the association between hepatic steatosis and LVMI using a general population sample. METHODS We analyzed data from the Study of Health in Pomerania. The study population comprised 1298 indivi...

BACKGROUND Adiponectin directly protects against cardiac remodeling. Despite this beneficial effect, most epidemiological studies have reported a negative relationship between adiponectin level and left ventricular mass index (LVMI). However, a positive relationship has also been reported in subjects at high risk of left ventricular hypertrophy (LVH). Based on these conflicting results, we hypo...

Methods Patients with severe AS had both pre-operative CMR and trans-thoracic echocardiography (TTE) within one week apart. From TTE, on top of the routine measurements, Zva was calculated as the sum of systolic blood pressure and the aortic valve continuous-wave Doppler mean gradient divided by the left ventricular stroke volume index. Patients were categorized into 2 groups according to their...

Background and Objectives:Chronic hypertension induces changes in the cardiac structure and function; however, the effects of transient hypertension are unclear. Pregnancy-induced hypertension (PIH) offers a natural and spontaneous model of this condition. Subjects and Methods:20 women, aged 30.3±5.1 years, with pregnancy-induced hypertension, defined as a blood pressure higher than 140/90 mmHg...

BACKGROUND Elevated left ventricular mass index (LVMI) and concentric left ventricular (LV) remodeling are related to adverse cardiovascular disease (CVD) events. The predictive utility of LV concentric remodeling and LV mass in the prediction of CVD events is not well characterized. METHODS AND RESULTS Framingham Heart Study Offspring Cohort members without prevalent CVD (n=1715, 50% men, ag...