Based on the crucial roles of oxidative stress and aldose reductase on diabetic complications and the protective effect against diabetic eye complication of purple waxy corn and ginger (PWCG) together with the synergistic effect concept, we aimed to determine anticataract and antiretinopathy effects of the combined extract of purple waxy corn and ginger (PWCG). The streptozotocin diabetics with...

PURPOSE To assess the crystalline lens opacity level by measuring ocular light scattering with a double-pass system. DESIGN Prospective, single-center, cross-sectional study. METHODS Two hundred fifty-three eyes of 135 patients referred for cataract evaluation were enrolled. Patients with corneal or retinal anomalies potentially impairing ocular transparency were excluded. Lens opacificatio...

PURPOSE To validate a new computer-aided diagnosis (CAD) imaging program for the assessment of nuclear lens opacity. METHODS Slit-lamp lens photographs from the Singapore Malay Eye Study (SiMES) were graded using both the CAD imaging program and manual assessment method by a trained grader using the Wisconsin Cataract Grading System. Cataract was separately assessed clinically during the stud...

Severe bilateral cataract was found in a 7 year-old naïve female cynomolgus monkey (Macaca fascicularis) 3 months before necropsy. During macroscopic examination, severe opacity and thinning of the lens were observed in both eyes. Histopathology revealed that the lens nuclei and majority of cortex lens fibers had disappeared and become excavated, while the lens fibers in the subcapsular area we...

purpose: to report a case of anterior segment eye deposits in a patient on long-term chlorpromazine therapy. case report: a 34 years old man had been on chlorpromazine therapy for 5 years with a total dose of 1,100 gram. since one year ago, he presented with gradual onset of decreased visual acuity in both eyes. slit-lamp examination revealed multiple fine yellow-brown deposits on the corneal e...

61 ethical problem, thereby taking it out of the realm of abstract ethical debate and into the real world. Dr. Shea, starting well with a quote by Dr. Ingelfinger, presents a well-written and absorbing essay on conflict between pharmacist and physician. In general this is a fine book dealing with highly relevant problems. The difficult questions at best have difficult answers, if they have any ...