نتایج جستجو برای: leukoreduction
تعداد نتایج: 138 فیلتر نتایج به سال:
Background: Several lines of evidence suggest the role of leukocyte in platelet activation. Since pro-inflammatory mediator CD40 ligand (CD40L) has been considered as a marker of platelet activation that reflecting platelet storage lesion (PSL), we evaluated the effect of leukoreduction processes on thereby the levels of expressed CD40L in Platelet Concentrates (PCs). Methods: In present stu...
INTRODUCTION Previous research has debated whether red blood cell (RBC) transfusion is associated with decreased or increased mortality in patients admitted to the intensive care unit (ICU). We conducted a systematic review and meta-analysis to assess the relationship of RBC transfusion with in-hospital mortality in ICU patients. METHODS We carried out a literature search on Medline (1950 thr...
UNLABELLED Previous experiments carried out in a sheep scrapie model demonstrated that the transfusion of 200 μl of prion-infected whole blood has an apparent 100% efficacy for disease transmission. These experiments also indicated that, despite the apparent low infectious titer, the intravenous administration of white blood cells (WBC) resulted in efficient disease transmission. In the study p...
BACKGROUND The transfusion of relatively older stored blood has been associated with an increased risk of multiple organ failure, infection, and death. It remains unknown whether this phenomenon is mitigated by transfusion of leukoreduced red cell units. The purpose of this study was to evaluate the influence of stored blood age on mortality in injured patients who universally received leukored...
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