Background: Chronic graft versus host disease (cGVHD) is a major cutaneous complication of bone marrow transplantation (BMT). Although milder forms of this process may be associated with a lower incidence of tumor recurrences, it is mandatory to develop a more efficient and less harmful therapeutic approach.Methods: This case-series study enrolled 7 patients diagnosed w...

Background: Chronic graft versus host disease (cGVHD) is a major cutaneous complication of bone marrow transplantation (BMT). Although milder forms of this process may be associated with a lower incidence of tumor recurrences, it is mandatory to develop a more efficient and less harmful therapeutic approach.Methods: This case-series study enrolled 7 patients diagnosed with chronic mucocutaneous...

A 15 year old boy admitted with fever for 10 days associated with altered sensorium. Clinical findings and relevant investigations (including CSF study) were consistent with the diagnosis of tubercular meningitis (TBM). He was put on oral corticosteroid and CAT-.I antitubercular drugs (ATD) (Thrice weekly dosage of INH: 600mg; Rifampicin: 450mg, Ethambutol: 1200mg, Pyrazinamide: 1500mg) [Day 1]...

This is a case report of an oral lichenoid drug reaction of the buccal sulci in a female diabetic patient who was on an anti-hypertensive drug, alpha-methyldopa (Aldomet) and an oral hypoglycaemic drug, chlorpropamide (Diabinese). The clinical features, histological findings and management are presented.

OBJECTIVE Lichen planus and lichenoid lesions affecting the oral cavity show similar clinico-pathological features creating a diagnostic dilemma. Hence, the aim of the present study was to establish a clinical and histopathological correlation in the diagnosis of oral lichen planus, based on the modified WHO diagnostic criteria of oral lichen planus and oral lichenoid lesions proposed by Van de...

BACKGROUND Dental materials, oral hygiene products and food additives may cause contact allergic reactions in the mouth with varied clinical presentation. Oral lichenoid lesions (lichen planus-like lesions) can be induced by hypersensitivity to dental restorative metals, acrylates, flavorings and other substances. AIM The aim of this study was to demonstrate contact allergy to dental material...

In the last few years there has been a special interest in the definition and classification of so called “premalignant oral diseases” (1). Frequent and controversial processes such as oral lichen planus and other similar oral lesions are included in this group (2, 3). Oral lichen planus is clinically characterized by white papular lineal lesions which show a reticular pattern, associated or no...

Lichenoid contact reaction is a type of delayed hypersensitivity to constituents derived from dental materials. It may occasionally transform into oral squamous cell carcinoma. A 62-year-male reported with the chief complaint wound in inner aspect right cheek for 2 weeks. On initial examination, diffuse erythematous area interspersed non- scrapable white striae was present on buccal mucosa and ...