Basal cell carcinoma (BCC) is a malignant tumor that may arise in skin damaged by sunlight and ionizing radiation in burn or vaccination scars. Clinical variants of BCC include nodular, morphea type, superficial and polypoid. Tattoo reactions are histologically diverse and can be classified in three main classes: 1) Allergic, granulomatous, and Lichenoid reactions; 2) Inoculation and infe...

Lichen planus, a chronic autoimmune, mucocutaneous disease affects the oral mucosa (oral lichen planus or OLP) besides the skin, genital mucosa, scalp and nails. An immune mediated pathogenesis is recognized in lichen planus although the exact etiology is unknown. The disease most commonly affects middle-aged females. Oral lichenoid reactions (OLR) which are considered variants of OLP, may be r...

UNLABELLED Oral lichen planus and lichenoid reactions are autoimmune type inflammatory conditions of the oral mucosa with similar clinical and histological characteristics. Recent data suggest that oral lichenoid reactions (OLR) present a greater percentage of malignant transformation than oral lichen planus (OLP). OBJECTIVE To compare the expression of bcl-2 and COX-2 in OLP and OLR. METHO...

INTRODUCTION The term Wolf's isotopic response refers to the appearance of a new skin disease at the site of an already healed, unrelated disease. In most cases, the initial disease is herpes zoster. Different diseases may subsequently develop on the same site. The most common isotopic responses are granulomatous and lichenoid reactions, infiltrations of hematologic diseases, skin tumors, and i...

Human oral mucosa is subjected to many noxious stimuli. One of these substances, in those who have restorations, is dental amalgam which contains mercury. This paper focuses on the local toxic effects of amalgam and mercury from dental restorations. Components of amalgam may, in rare instances, cause local side effects or allergic reactions referred to as oral lichenoid lesions (OLLs). OLLs to ...

BACKGROUND The role of contact allergy in oral cavity disease processes is unknown. OBJECTIVE We sought to determine the prevalence of contact allergy to flavorings, preservatives, dental acrylates, medications, and metals in patients with oral disease. METHODS Patients were tested with an 85-item oral antigen screening series. Data were analyzed retrospectively. RESULTS We evaluated 331 ...