نتایج جستجو برای: like factor 2b klf2b

تعداد نتایج: 1435886  

Journal: :Chest 2012
Clive Kearon Elie A Akl Anthony J Comerota Paolo Prandoni Henri Bounameaux Samuel Z Goldhaber Michael E Nelson Philip S Wells Michael K Gould Francesco Dentali Mark Crowther Susan R Kahn

BACKGROUND This article addresses the treatment of VTE disease. METHODS We generated strong (Grade 1) and weak (Grade 2) recommendations based on high-quality (Grade A), moderate-quality (Grade B), and low-quality (Grade C) evidence. RESULTS For acute DVT or pulmonary embolism (PE), we recommend initial parenteral anticoagulant therapy (Grade 1B) or anticoagulation with rivaroxaban. We sugg...

2015
Ashutosh Shukla Debajit Dey Kamalika Banerjee Anshu Nain Manidipa Banerjee

Viroporins are virally encoded, membrane-active proteins, which enhance viral replication and assist in egress of viruses from host cells. The 2B proteins in the picornaviridae family are known to have viroporin-like properties, and play critical roles during virus replication. The 2B protein of Hepatitis A Virus (2B), an unusual picornavirus, is somewhat dissimilar from its analogues in severa...

2012
Clive Kearon Elie A. Akl Samuel Z. Goldhaber

2.1. In patients with acute DVT of the leg treated with vitamin K antagonist (VKA) therapy, we Background: This article addresses the treatment of VTE disease. Methods: We generated strong (Grade 1) and weak (Grade 2) recommendations based on highquality (Grade A), moderate-quality (Grade B), and low-quality (Grade C) evidence. Results: For acute DVT or pulmonary embolism (PE), we recommend ini...

Journal: :iranian journal of neurology 0
masoud mehrpour associate professor of neurology, iran university of medical science (iums), tehran, iran. hessam rahatlou resident of neurosurgery, iran university of medical science (iums), tehran, iran. negar hamzehpur medical doctor, iran university of medical science (iums), tehran, iran. sahand kia medical doctor, iran university of medical science (iums), tehran, iran. mahdi safdarian medical doctor, iran university of medical science (iums), tehran, iran.

background:  the aim of this study was to evaluate whether higher serum levels of igf-i in the acute phase of ischemic stroke are associated with less severe strokes and better functional outcome in a period of one year follow up. methods: from october 2014 to august 2015, patients with the diagnosis of acute ischemic stroke admitted to the stroke unit of firoozgar hospital entered this prospec...

Journal: :hepatitis monthly 0
asghar khoshnood department of internal medicine, shahid sadoughi hospital, shahid sadoughi university of medical sciences, ir iran +98-3518224000, [email protected]; department of internal medicine, shahid sadoughi hospital, shahid sadoughi university of medical sciences, ir iran +98-3518224000, [email protected] mohsen nasiri toosi department of gastroenterology, imam khomeini hospital, tehran university of medical sciences, ir iran mohammad jafar faravash department of gastroenterology, imam khomeini hospital, tehran university of medical sciences, ir iran alireza esteghamati department of endocrinology, imam khomeini hospital, tehran university of medical sciences, ir iran hosein froutan department of gastroenterology, imam khomeini hospital, tehran university of medical sciences, ir iran hadi ghofrani department of gastroenterology, imam khomeini hospital, tehran university of medical sciences, ir iran

results 100 patients with cirrhosis with a male to female ratio of 63:37 and a mean age of 44.4 ± 15 years were enrolled in the study. median igf-1 was 92.95 ± 91.51 ng/ml. 14 patients (14%) had igf-1 within normal limits while 86 patients (86%) had abnormal igf-1 levels. in all patients the correlation coefficient between igf-1 and meld was -0.317 (p = 0.001) and 0.478 between igf-1 and child-...

2016
Zixiang Zhu Guoqing Wang Fan Yang Weijun Cao Ruoqing Mao Xiaoli Du Xiangle Zhang Chuntian Li Dan Li Keshan Zhang Hongbing Shu Xiangtao Liu Haixue Zheng

The role of retinoic acid-inducible gene I (RIG-I) in foot-and-mouth disease virus (FMDV)-infected cells remains unknown. Here, we showed that RIG-I inhibits FMDV replication in host cells. FMDV infection increased the transcription of RIG-I, while it decreased RIG-I protein expression. A detailed analysis revealed that FMDV leader proteinase (Lpro), as well as 3C proteinase (3Cpro) and 2B prot...

Journal: :Molecular pharmacology 2006
Sergey Ryzhov Anna E Goldstein Italo Biaggioni Igor Feoktistov

Human mast cells express functional A(2A) and A(2B) adenosine receptors. However, only stimulation of A(2B), not A(2A), leads to secretion of interleukin (IL)-4, an important step in adenosine receptor-mediated induction of IgE synthesis by B-cells. In this study, we investigate intracellular pathways that link stimulation of A(2B) receptors to IL-4 up-regulation in HMC-1 mast cells. Both A(2A)...

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