like tyrosine kinase 3

نتایج جستجو برای: like tyrosine kinase 3

تعداد نتایج: 2524300 فیلتر نتایج به سال:

Absence of Fms-like tyrosine kinase 3 ligand (Flt3L) signalling protects against collagen-induced arthritis

Journal: :Annals of the Rheumatic Diseases 2013

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Sorafenib in Relapsed AML With FMS-Like Receptor Tyrosine Kinase-3 Internal Tandem Duplication Mutation

Journal: :Journal of the National Comprehensive Cancer Network 2015

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Tyrosine kinase fusion genes in pediatric BCR-ABL1-like acute lymphoblastic leukemia

2017

Judith M. Boer Elisabeth M.P. Steeghs João R.M. Marchante Aurélie Boeree James J. Beaudoin H. Berna Beverloo Roland P. Kuiper Gabriele Escherich Vincent H.J. van der Velden C. Ellen van der Schoot Hester A. de Groot-Kruseman Rob Pieters Monique L. den Boer

Approximately 15% of pediatric B cell precursor acute lymphoblastic leukemia (BCP-ALL) is characterized by gene expression similar to that of BCR-ABL1-positive disease and unfavorable prognosis. This BCR-ABL1-like subtype shows a high frequency of B-cell development gene aberrations and tyrosine kinase-activating lesions. To evaluate the clinical significance of tyrosine kinase gene fusions in ...

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Preeclampsia and Soluble fms-Like Tyrosine Kinase 1

Journal: :The Journal of Clinical Endocrinology & Metabolism 2009

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PI3Kδ inhibitor idelalisib in combination with BTK inhibitor ONO/GS-4059 in diffuse large B cell lymphoma with acquired resistance to PI3Kδ and BTK inhibitors

2017

Anella Yahiaoui Sarah A. Meadows Rick A. Sorensen Zhi-Hua Cui Kathleen S. Keegan Robert Brockett Guang Chen Christophe Quéva Li Li Stacey L. Tannheimer

Activated B-cell-like diffuse large B-cell lymphoma relies on B-cell receptor signaling to drive proliferation and survival. Downstream of the B-cell receptor, the key signaling kinases Bruton's tyrosine kinase and phosphoinositide 3-kinase δ offer opportunities for therapeutic intervention by agents such as ibrutinib, ONO/GS-4059, and idelalisib. Combination therapy with such targeted agents c...

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