OBJECTIVES: To highlight the importance of embolectomy in patients with acute embolic limb ischemia. STUDY DESIGN: Descriptive analytic study. PLACE AND DURATION OF STUDY: The Department of Vascular Surgery, Combined Military Hospital Lahore, from July 2008 to April 2015. PATIENTS AND METHODS: 256 consecutive patients having acute limb ischemia who underwent embolectomy were included in this st...

Lower limb ischemia caused by multiple stenosis of the thoracoabdominal aorta is one of the rare clinical manifestations of Takayasu arteritis. The optimal management of such mid-aortic syndrome related with Takayasu arteritis has not been established to date. Here we report a case of extra-anatomic aortic bypass through minimally invasive techniques to treat lower limb ischemia caused by Takay...

Unlike epidemics in past centuries, patients suffering from peripheral vascular ischemia related to ergotism now rarely lose a limb because of vasodilator therapies. We report a patient with ischemia from ergotamine tartrate who failed to recover with medical therapy, resulting in limb amputation.

Background Recommendations of clinical guidelines for the treatment of critical limb ischemia (CLI) are based on randomized controlled trials [1]. Surgery using different grafts (venous or prosthetic) is in competition with percutaneous angioplasty. Progress of endoluminal techniques has brought certain authors to think that angioplasty is now the first treatment of critical limb ischemia [2].

traumatic injuries to the subclavian-axillary artery, although uncommon, are associated with high morbidity and mortality rates if not managed promptly. the emergence of endovascular techniques offers an alternative to the surgical management of these injuries. we herein present 4 cases of traumatic subclavian-axillary artery injury with limb ischemia successfully managed via the endovascular a...

OBJECTIVE CTX0E03 (CTX) is a clinical-grade human neural stem cell (hNSC) line that promotes angiogenesis and neurogenesis in a preclinical model of stroke and is now under clinical development for stroke disability. We evaluated the therapeutic activity of intramuscular CTX hNSC implantation in murine models of hindlimb ischemia for potential translation to clinical studies in critical limb is...

ACUTE limb ischemia is any sudden decrease or worsening in limb perfusion that causes a potential threat to limb viability (1). Acute peripheral arterial occlusion may be caused by in situ thrombosis or embolus. In this article, the term “thrombus” will be used to describe arterial occlusion caused by in situ thrombosis or embolus. Percutaneous or “open” surgical techniques can be used to remov...

In the present experiments the effect of long-term peripheral ischemia on the capillary of two hind limb skeletal muscles was investigated in spontaneously hypertensive rats. Furthermore, the effect of antihypertensive therapy on changes in capillarity and on the previously observed hyperreactivity of the ischemic vascular bed to vasoconstrictors was investigated in perfused hind limbs of rats ...