Certain DNA sequence motifs and structures can promote genomic instability. We have explored instability induced in mouse cells by long inverted repeats (LIRs). A cassette was constructed containing a herpes simplex virus thymidine kinase (tk) gene into which was inserted an LIR composed of two inverted copies of a 1.1-kb yeast URA3 gene sequence separated by a 200-bp spacer sequence. The tk ge...

In this article, we study the new streamline diffusion finite element for treating the linear second order hyperbolic initial-boundary value problem. We prove a posteriori $ L^2(L^2)$ and error estimates for this method under minimal regularity hypothesis. Test problem of an application of the wave equation in the laser is presented to verify the efficiency and accuracy of the method.

Objective: To elucidate the value of early computed tomographic (CT) signs of stroke in predicting the occlusion site in the cerebral arteries. Patients: 105 consecutive patients with acute embolic stroke affecting the anterior circulation. Methods: Four early signs were evaluated on cranial CT within six hours of stroke onset: loss of the insular ribbon (LIR); attenuation of the lentiform nucl...

Using variational analysis, we study the linear regularity for a collection of finitely many closed sets. In particular, we extend duality characterizations of the linear regularity for a collection of finitely many closed convex sets to the possibly nonconvex setting. Moreover the sharpest linear regularity constant can also be dually represented under the subsmoothness assumption.

in this work, removal of c. i. acid red 14 was investigated by pumice stone as a low cost adsorbent. various parameters such as initial dye solution, contact time and ph were studied. removal of dye were increased by increasing of contact time and initial dye solution and deceased by increasing of ph. three isotherm models were studied. linear and non-linear regression analyses were used for de...

Autophagy recycles cellular components and defends cells against intracellular pathogens. While viruses must evade autophagocytic destruction, some viruses can also subvert autophagy for their own benefit. The ability of influenza A virus (IAV) to evade autophagy depends on the Matrix 2 (M2) ion-channel protein. We show that the cytoplasmic tail of IAV M2 interacts directly with the essential a...

Results are presented for [C ii] 158μm line fluxes observed with the Herschel PACS instrument in 112 sources with both starburst and active galactic nucleus (AGN) classifications, of which 102 sources have confident detections. Results are compared with mid-infrared spectra from the Spitzer Infrared Spectrometer and with Lir from IRAS fluxes; AGN/starburst classifications are determined from eq...