The delivery method of [continuous (CONT) vs. every other day or intermittent (INT)] a glucogenic precursor (GP) which was contained glycerin (500 g/kg), mono-propylene glycol (250 g/kg), calcium propionate (150 g/kg), niacin (1 g/kg) and sulfate-Co (350 mg/kg) on performance, selected blood metabolites and liver enzymes were evaluated. Twenty-four multiparous Holstein fresh cows were ...

conclusions liver metastasis of neuroendocrine tumors in iran presents in a very similar manner as that seen in western countries. in about 89% of cases with liver-net, complete imaging, clinical, and pathological studies can help to identify the primary origin of the liver-net, which is very important in the patient’s management. results the most common primary site of metastatic gi-net to the...

In hepatocellular carcinoma (HCC), somatic genome-wide DNA mutations are numerous, universal and heterogeneous. Some of these somatic mutations are drivers of the malignant process but the vast majority are passenger mutations. These passenger mutations can be deleterious to individual protein function but are tolerated by the cell or are offset by a survival advantage conferred by driver mutat...

BACKGROUND Chronic hepatitis B virus (HBV) infection leads to liver fibrosis, which is a major risk factor in hepatocellular carcinoma (HCC) and an independent risk factor of recurrence after HCC tumor resection. The HBV genome can be inserted into the human genome, and chronic inflammation may trigger somatic mutations. However, how HBV integration and other genomic changes contribute to the r...

BACKGROUND & AIMS Heterozygous germline mutations in PRKCSH cause autosomal dominant polycystic liver disease (PCLD), but it is not clear how they lead to cyst formation. We investigated whether mutations in cyst epithelial cells and corresponding loss of the PRKCSH gene product (hepatocystin) contributed to cyst development. METHODS Liver cyst material was collected through laparoscopic cyst...

It has been suggested that enlarged values of morphological measurements manifesting obesity intensify the risk of sleep disturbances. The main goal of this work was to find a set of predictor morphometric variables that best distinguish between the mutually exclusive groups of interest, the well and the ill – i.e., those who suffer from obstructive sleep apnoea (OSA) syndrome, and healthy pati...

In this study, Channa punctatus was treated with sub-lethal concentration of cypermethrin (6.6 μg/L) for 5, 10 and 15 days and its effect on total CYP 450 and the activity of hepatic CYP450 isoforms measured. Total CYP450 content and CYP1A mediated EROD activity was significantly induced (p<0.05) in all three treated groups compared to control whereas only 15 days treated group showed significa...

This work was carried out to verify the effect of a glyphosate-based herbicide on Jundiá hormones (cortisol, 17β-estradiol and testosterone), oocyte and swim-up fry production. Earthen ponds containing Jundiá females were contaminated with glyphosate (3.6mg/L); blood samples were collected from eight females from each treatment immediately before, or at 1, 10, 20, 30 and 40 days following conta...

This study attempts to look into the energetic status of demersal fish species with their maturity stages and evaluate their energetic condition. Demersal fish species from wild were captured, total length and weight of each fish were measured and gonads were observed, weighted and collected with fish flesh. Gonadosomatic index, water content of gonad and flesh and gonadal and somatic caloric v...