introduction: kikuchi-fujimoto disease or histocytic necrotizing lymphadenitis is a rare, benign, self-limited condition characterized by constitutional symptoms, lymphadenopathy, and skin lesions and often affects young adult females.the etiology is unknown although viruses and autoimmune mechanisms has been suggested. diagnosis is fundamentally based on the affected lymph node biopsy.the pati...

Intralesional Th2 responses preceded the development of Th1 responses in localized cutaneous leishmaniasis due to Leishmania guyanensis. Although the number of parasites increased in Th2 lesions, no correlation was found between the levels of cytokine expression and the number of parasites. In contrast, the decreased number of parasites in Th1 lesions is negatively correlated to gamma interfero...

OBJECTIVES/HYPOTHESIS The whole-blood interferon (IFN)-γ release assay (IGRA) has been studied mainly for diagnosing latent tuberculosis (TB). We prospectively evaluated its diagnostic usefulness in patients with suspected cervical TB lymphadenitis. STUDY DESIGN Prospective cohort study. METHODS An IGRA was performed in subjects with suspected TB lymphadenitis. To evaluate the diagnostic pe...

based effective treatment (9). Surgical excision remains controversial because of potentially high rates of significant scarring (10). For nonsuppurative lymphadenitis, a watch-and-wait approach is recommended because most resolve rapidly (8). Given our findings, the National TB Program in Georgia subsequently created a management protocol. This protocol recommends no intervention for nonsuppur...

Lymphadenopathy is most commonly encountered problems in clinical practice. Various etiological factors can cause lymphadenopathy. Cytomorphological study of lymphadenopathy a window for diagnosis many disease processes. Aspiration cytology provides reliable, safe, rapid and economical method screening the patients with accuracy. It differentiate neoplastic from non-neoplastic lesions therefore...

Lymphadenitis and abscess formation are the most common side effects of vaccination with Bacille Calmette Guerin (BCG). The lower the child's age at the time of vaccination, the higher the incidence of BCG lymphadenitis tends to be. Although various therapeutic approaches are in use for the treatment of BCG lymphadenitis, there is no consensus on which of them is optimal. This study aimed to de...

BACKGROUND Cytochrome P450s (CYP450s) are hemoproteins catalysing diverse biochemical reactions important for metabolism of xenobiotics and synthesis of physiologically important compounds such as sterols. Therefore, they are functionally important for survival of invading pathogens. One such opportunistic pathogen Leishmania donovani causes visceral leishmaniasis worldwide, which is an importa...

Tuberculosis is a very serious disease and incidence is once again on the rise. Lymph node tuberculosis is one of the most common extrapulmonary manifestations of tuberculosis. In differential diagnosis of chronic, painless cervical lymphadenopathy, cervical tuberculous lymphadenitis should be kept in mind. A high index of suspicion is needed for diagnosis of tuberculous lymphadenitis, which is...

Sixty eight patients with localized cutaneous leishmaniasis from an area with Leishmania (Viannia) braziliensis transmission had cultures performed with a modified Marzochís vacuum aspiratory puncture technique to establish sensitivity and contamination rate with this new method. Overall sensitivity of three aspirates was 47.1%; (CI95% 39.4; 59.4) significantly greater than the sensitivity of a...