The objective of this study was to compare the bioefficacy of L-lysine sulfate relative to L-lysine⋅HCl for 10 to 20 kg pigs. Two experiments were conducted to determine the bioefficacy of the two sources of lysine using daily gain, feed conversion, plasma urea nitrogen and nitrogen retention as the response criteria. In experiment 1, 168 crossbred barrows (Landrace×Large White), weaned at 28±3...

Production of lysine by Corynebacterium glutamicum (PTCC 1532) from different agricultural by-products (molasses and pulpy waste date) was compared to glucose as raw materials. For this purpose, ammonium sulphate was selected as a constant nitrogen source. The effect of different nitrogen sources was also investigated with glucose as a constant carbon source. The production of L-lysine was exam...

The conversion of l-[U-(14)C]lysine into carnitine was demonstrated in normal, choline-deficient and lysine-deficient rats. In other experiments in vivo radioactivity from l-[4,5-(3)H]lysine and dl-[6-(14)C]lysine was incorporated into carnitine; however, radioactivity from dl-[1-(14)C]lysine and dl-[2-(14)C]lysine was not incorporated. Administered l-[Me-(14)C]methionine labelled only the 4-N-...

A steady-state level of about 240 nmol/mg (dry wt) occurs during lysine transport in Saccharomyces cerevisiae. No subsequent efflux of the accumulated amino acid was detected. Two transport systems mediate lysine transport, a high-affinity, lysine-specific system and an arginine-lysine system for which lysine exhibits a lower affinity. Preloading with lysine, arginine, glutamic acid, or asparti...

Freely occurring alpha-l-aspartyl-l-histidine, beta-alanyl-l-histidine (carnosine), alpha-l-aspartyl-alpha-l-lysine, l-asparaginyl-alpha-l-lysine, alpha-l-glutamyl-alpha-l-lysine, l-isoleucyl-alpha-l-lysine, l-seryl-alpha-l-lysine, l-valyl-alpha-l-lysine and glycyl-alpha-l-lysyl-alpha-l-lysine were identified in young larvae (second and third instars) of the blowfly (Phormia regina).

Lysine propionylation and butyrylation are protein modifications that were recently identified in histones. The molecular components involved in the two protein modification pathways are unknown, hindering further functional studies. Here we report identification of the first three in vivo non-histone protein substrates of lysine propionylation in eukaryotic cells: p53, p300, and CREB-binding p...

lysine metabolism has been measured in rats fed a diet low in trimethyl-lysine and carnitine (Davis & Hoppel, 1983, 1986). Under these steady-state conditions, the total body trimethyl-lysine content is similar to the total body carnitine content. The tissue distribution of peptide-linked and free trimethyl-lysine shows that approximately 68% of the total trimethyl-lysine is present in skeletal...

Two experiments were conducted to compare the nutritional adequacy of a genetically improved high-lysine, high-oil corn (HLHOC; .408% lysine, 6.21% fat, as-fed basis) and a high-oil corn (HOC; .289% lysine, 5.97% fat, as-fed basis) for young growing pigs. Experiment 1 used four non-littermate barrows (initially 20.0 kg BW) fitted with ileal T-cannulas in a crossover-designed digestion study. Th...