Radioactively labeled thymidine (TdR) has been used extensively to measure bacterial production in aquatic environments, but critical assumptions of the TdR technique often have gone untested. In this study of a coastal marine sediment, the metabolic fate of methyl [3H]TdR and methyl [14C]TdR was at variance with the assumptions necessary for determining bacterial production. Only 2% of incorpo...

While confirming the long held view that “viruses do not closely imitate the use of the [host’s] ... codon catalogue” (Grantham et al., 1986), it is nevertheless considered a “surprising finding” that “despite having the ability to infect the same host, many mycobacteriophages share little or no genetic similarity” (i.e. similarity in their “GC contents and codon utilization patterns;” Esposito...

Neurons from bullfrog sympathetic ganglia were voltage-clamped using a single microelectrode in Ringer solution with tetrodotoxin. The M-current (Adams et al. 1982 a) was markedly reduced during the rhythmic outward potassium current induced by caffeine (1-5 mM). This indicates that an elevation of the intracellular concentration of calcium ions by caffeine not only activates the calcium-activa...

The muscarinic acetylcholine receptor (mAChR) of both brain and myocardium is an integral membrane sialoglycoprotein of molecular mass approx. kDa (Birdsall r t al., 1979; Berrie ef al., 1985h; Haga & Haga, 1985; Peterson et al., 1986). The carbohydrate moiety has been estimated to contribute between 6 and 20 kDa to the overall molecular mass (Rauh CI al., 1986; Peterson et al., 1986). Variatio...

GABA-receptor-operated chloride ion channels are widely distributed on membranes of insect nervous tissue (for a review, see Sattelle, 1990). For example, in the cockroach Periplaneta americana radioligand binding (Lummis and Sattelle, 1986), autoradiography (Lummis and Sattelle, 1985) and GABA-activated ^Cl flux (Wafford et al. 1987) studies have demonstrated the presence of GABAoperated chlor...

1 Dasgupta A, Metha AC, Wang KP. Transbronchial needle aspiration. Semin Respir Crit Care Med 1997; 18:571–581 2 Patelli M, Lazzari Agli L, Poletti V, et al. Role of fiberscopic transbronchial needle aspiration in the staging of N2 disease due to non-small cell lung cancer. Ann Thorac Surg 2002; 73:407–411 3 Kucera RF, Wolfe GK, Perry ME. Hemomediastinum after transbronchial needle aspiration [...

Neurite outgrowth from isolated, identified molluscan (Helisoma trivolvis) neurons in culture can be suppressed by neurotransmitters and electrical activity, both of which increase intraneuronal Ca2+ levels (Haydon et al., 1984; Cohan et al., 1986, 1987). We explored the possibility of a causal relationship between Ca2+ influx from the cell exterior and neurite outgrowth using a spectrum of pha...

Buspirone hydrochloride is a now nonbenzodiazepine, non-barbiturate, non-narcotic t ranquil izer . It is an 'agaspirodecanedione", lipophilic and a heterocyclic compound. Absorption of buspironc from gastrointestinal tract is virtually complete. Peak plasma level is achieved in less, than one hour after a single dose. T h e elimination half life of the drug ranges from 2 to 8 hours in healthy s...