In this article we describe the preparation and characterization of a water-triggered shape memory polymer (SMP) family, PCL–PEG based thermoplastic polyurethanes (TPUs). Upon immersion in water, water molecules selectively swelled the hydrophilic PEG domains, resulting in durable hydrogels with strain-to-failure values greater than 700%. Dry samples fixed in a temporary shape underwent watertr...

This work aimed to develop a subcutaneous implant for prolonged delivery of LEVO treat hypothyroidism. could overcome challenges with patient compliance and co-administration improve treatment this condition. For purpose, implants were produced by solvent casting mixtures poly(caprolactone) (PCL), poly(ethylene glycol) (PEG) sodium. These contained PCL differing molecular weight, PEG different ...

Magnetic nanoparticles have been highly regarded because of their unique properties, such as hyperthermia, medicine control release, and diagnostic applications. The main aim of the current paper is to offer a new system for the modification of Fe3O4 (SPIONs) superparamagnetic nanoparticles physically and chemically with polymers through physical retention. These modified nanoparticles have bee...

This study aims to hydrophilize thermoplastic polyurethane (TPU) surface via selective segregation of amphiphilic block copolymers from bulk TPU matrix, namely “inverted grafting-to” approach. To this end, hydrophilic poly(ethylene glycol) (PEG) polymer chain was employed in either diblock (polycaprolactone-b-poly(ethylene (PCL-b-PEG)) or triblock (poly(ethylene glycol)-b-poly(propylene glycol)...

Stealth nanoparticles made of polymer micelles are ideal drug carriers for targeted drug delivery, but their stability is critical for intravenous applications. We found that core-surfacecrosslinked nanoparticles (SCNp) made from amphiphilic brush copolymers had greatly enhanced stability. The surface of the SCNps can be easily tailored by using different chains. The amphiphilic brush copolymer...