10.2217/14750708.4.2.167 © 2 Evaluation of: Yang Z, Camp NJ, Sun H et al.: A variant of the HTRA1 gene increases susceptibility to age-related macular degeneration. Science 314(5801), 992–993 (2006) [1]. Age-related macular degeneration is a common cause of visual loss in the elderly, yet the genetic basis for this disease is poorly understood. Linkage studies show a major susceptibility locus ...

Macular degeneration or often called Age-related Degeneration (AMD) is a degenerative disease that attacks the center of vision in retina, namely macula. In an effort to prevent progression AMD, consuming antioxidants has been shown inhibit AMD development process. Although currently there no definite number sufferers Indonesia, it estimated will continue increase. Carotenoids are one antioxida...

Age related macular degeneration (AMD) is an eye related disease which leads to blindness as the disease progresses. Hence it is important to detect the disease early for timely treatment. This paper discusses about the identification of macular degeneration using multiresolution techniques and texture analysis from the fundus images of the eye. Images are analyzed at different scales and resol...

True vitelliform dystrophy rarely appears in the adult population. We describe 10 cases in adults of bilateral vitelliform lesions clinically mistaken for Best's disease. Fluorescein angiography is a useful tool in distinguishing this dystrophy from Best's disease or other diseases. The angiographic findings suggest pigment epithelial disease. Adult vitelliform degeneration may lead to dry atro...

One thousand black African and 380 white Caucasian patients over the age of 50 were examined for evidence of age-related macular changes, namely, drusen, pigment epithelial atrophy, and disciform macular degeneration. Drusen and pigment epithelial changes were found to occur twice as commonly in Caucasians as in Africans; there was a much greater difference in the prevalence of disciform macula...

A recent genome-wide association study has reported three newly identified susceptible loci (rs2842992 near the gene SOD2, rs1789110 near the gene MBP and rs722782 near the gene C8orf42) to be associated with the geographic atrophy subtype of age-related macular degeneration in European-descent population. We investigated the correlation between these variants and advanced age-related macular d...

Key Terms Anesthesia Paresthesia Hypoesthesia Hyperesthesia Analgesia Hypalgesia Remedial treatment Compensatory treatment Vision Visual perception Visual acuity Oculomotor control Visual fields Visual attention Visual scanning Pattern recognition Visual memory Visual cognition Myopia Hyperopia Presbyopia Astigmatism Cataracts Macular degeneration Glaucoma Hypertension Diabetic retinopathy Macu...

OCT angiography has improved the ability to identify silent or nonexudative neovessels in age-related macular degeneration. This promotes a rapid advancement diagnosis and necessity expand our management decisions. context is presented biomarkers are discussed.