The maf oncogene encodes a bZip nuclear protein which recognizes sequences related to an AP-1 site either as a homodimer or as heterodimers with Fos and Jun. We describe here a novel maf-related gene, mafG, which shows extensive homology with two other maf-related genes, mafK and mafF. These three maf-related genes encode small basic-leucine zipper proteins lacking the trans-activator domain of...

Xanthomonas is one of the most widespread phytobacteria, causing diseases on a variety of agricultural plants. To develop novel control techniques, knowledge of bacterial behavior inside plant cells is essential. Xanthomonas campestris pv. campestris, a vascular pathogen, is the causal agent of black rot on leaves of Brassicaceae, including Arabidopsis thaliana. Among the X. campestris pv. camp...

Description Attempts to control bovine tuberculosis in GB are hampered by lack of scientific knowledge in several key areas: (1). A true picture of the pathology, immunology and clinical pathology of reactor cattle; (2). The extent to which ongoing infection in herds is due to cattle to cattle spread being maintained by animals falsely testing negative to the skin test. By undertaking detailed ...

TCF11 (also known as Nrf1 and LCR-F1) is a basic-region leucine-zipper (b-ZIP) transcription factor that is essential during embryonic development. We have carried out expression analysis at a number of developmental stages and find that while there is some localized elevated expression between 8 and 9 days post coitum (dpc), the gene is widely expressed with a constant level of mRNA transcript...

Partial sequences of farnesyl diphosphate (FPP) synthase genes derived from the Rhodobacter-Rhodovulum group and from the Rhodopseudomonas palustris-Bradyrhizobium japonicum group of the alpha-Proteobacteria were subjected to phylogenetic analysis to investigate the relationships of phototrophic and non-phototrophic bacteria in the alpha-Proteobacteria . The four Rhodovulum species formed a mon...

Farnesyl diphosphate (FPP) synthase is essential not only for phototrophic bacteria in carotenoid biosynthesis, but also for non-phototrophic bacteria in the biosynthesis of physiologically important compounds. The gene encoding FPP synthase was assessed as a molecular marker to investigate the intermingled relationship between the phototropic and non-phototropic bacteria in the alpha-Proteobac...

The present paper reports the protocol and some outcomes of a feasibility study of the British National Diet and Nutrition Survey (NDNS) of people aged 65 years or over. The feasibility study was carried out in February and March 1994 in order to develop and test all components of the protocol for the main survey. The fieldwork for the main survey takes place over 12 months and began in October...

Members of the small Maf family (MafK, MafF, and MafG) are basic region leucine zipper (bZip) proteins that can function as transcriptional activators or repressors. The dimer compositions of their DNA binding forms determine whether the small Maf family proteins activate or repress transcription. Using a yeast two-hybrid screen with a GAL4-MafK fusion protein, we have identified two novel bZip...

MafF interacting protein (MIP) is product of a candidate gene related to liver cancer development and progression. Here, we demonstrated that MIP could inhibit the proliferation of cancer cells through colony formation assays, and the inhibition ability of MIP to SMMC7721 cells was notably stronger than to HeLa cells. Using pGBKT7-MIP as bait, a human placenta cDNA library was screened using ye...