Here we demonstrate that the anomalous magnetic properties of iron oxide nanoparticles are correlated with defects in their interior. We studied the evolution of microstructure and magnetic properties of biphasic core|shell Fe(1-x)O|Fe(3-δ)O4 nanoparticles synthesized by thermal decomposition during their topotaxial oxidation to single-phase nanoparticles. Geometric phase analysis of high-resol...

Background & Aims: In spite of frequent produce and use of magnetic nanoparticles in biological fields, there are few studies on their side effects, especially under in-vivo conditions. Method: In this research, the effect of the single-dose intraperitoneal injection of DMSA (dimercaptosuccinic acid) coated magnetic iron oxide nanoparticles (Fe3O4) in different doses (50, 100, 200 and 300 mg/kg...

Magnetic nanoparticles (MNPs) are very important systems with potential use in drug delivery systems, ferrofluids, and effluent treatment. In many situations, such as in biomedical applications, it is necessary to cover inorganic magnetic particles with an organic material, such as polymers. A superparamagnetic nanocomposite Fe3O4/poly(maleic anhydride-co-acrylic acid) P(MAH-co-AA) with a core/...

background: ultrasmallsuperparamagnetic iron oxide (uspio) nanoparticles are used as blood pool contrast agent for magnetic resonance angiography and perfusion imaging. our aim in this study was to investigate the effect of the two coating types of iron oxide nanoparticles on the relationship between nanoparticles concentration and signal intensity (si) in t1-weighted mr images.   methods : dif...

in this work, we report synthesis of surface modified superparamagnetic iron oxide nanoparticles (spion) by co-precipitation method using feso4.7h2o and fe2(so4)3.5h2o as precursors and trisodium citrate dihydrate as surfactant. surface modification of the as prepared samples was performed in pot by sol-gel precipitation method using tetraethoxysilane (teos). the structure, morphology, and magn...

recombinant protein purification is a kind of sensitive and expensive method in genetics engineering. genetic manipulation leads to the expression of various proteins; it should be isolated with high purity finally. differed methods for protein purification are categorized, based on cast, quality, easy work and side effect of protein. in this article, we are investigating his his-tag protein pu...

in this research, the magnetite nanoparticles (fe304) were prepared by coprecipitation of fe3+ andfe solution in alkaline medium. two kinds of surfactants, cetyl tri methyl ammonium bromide(ctab) and cetyl pyridinum chloride (cpc) were used in the synthesis. fe304 nanoparticles werecoated with human serum albumin (hsa) and bovine serum albumin (bsa). characteristics ofcoated magnetic nanopartic...

FePt/iron oxide core/shell nanoparticles are synthesized by a two step polyol process with 1,2hexadecanediol as the reducing reagent. Monodispersed 2.6-nm FePt nanoparticles are first obtained by reduction of iron(III) acetylacetonate and platinum(II) acetylacetonate. These preformed FePt nanoparticles are then used as seeds and an iron oxide shell is formed in the second synthesis step. The ro...

Iron oxide nanoparticles are smart materials that have been commonly used in medicine for diagnostic imaging, drug delivery, and therapeutic applications. In this study, Iron oxide nanoparticles and doxorubicin hydrochloride, were absorbed into poly (D, L-lactic-co-glycolic acid) poly (ethylene glycol) (PLGA-PEG) nanoparticles for narrow behavior. PLGA:PEG triblock copolymers were synthesized b...

The iron oxide nanoparticles have been synthesized in co-precipitation method using aqueous solution of ferric and ferrous ions with sodium salt. The synthesis of iron-oxide nanoparticles were validated by UV-Visible spectroscopy which showed higher peak at 370 nm as valid standard reference. An average size of iron oxide nanoparticle found by diffraction light scattering (DLS) particle size an...