Au- and iron-based magnetic nanoparticles (NPs) are promising NPs for biomedical applications due to their unique properties. The combination of a gold coating over a magnetic core puts together the benefits from adding the magnetic properties to the robust chemistry provided by the thiol functionalization of gold. Here, the use of Au-coated magnetic NPs for molecular detection of a single meth...

Targeted therapy is a method owing to its limited side effect profile, particularly in cancer treatment. Magnetic hyperthermia, which is induced by nanoparticles (NPs) conjugated with targeting agents, can be useful in combination with chemo- or radiotherapy. In this paper, we constructed dextran-coated ferric oxide NPs conjugated with specific anti-human epidermal growth factor receptor (HER2)...

Magnetic Particle Imaging (MPI) is a quantitative mass-sensitive, tracer-based imaging technique, with potential applications in various cellular imaging applications. The spatial resolution of MPI, in the first approximation, improves by decreasing the full width at half maximum (FWHM) of the field-derivative of the magnetization, dm/dH of the nanoparticle (NP) tracers. The FWHM of dm/dH depen...

Biocompatible superparamagnetic iron oxide nanoparticles (NPs) through smart chemical functionalization of their surface with fluorescent species, therapeutic proteins, antibiotics, and aptamers offer remarkable potential for diagnosis and therapy of disease sites at their initial stage of growth. Such NPs can be obtained by the creation of proper linkers between magnetic NP and fluorescent or ...

conclusions based on our results, the administration of fe3o4-nps causes dose dependent adverse effects on liver. background because of their unique magnetic properties, fe3o4 nanoparticles (fe3o4-nps) have extensive applications in various biomedical aspects. investigation of the possible adverse aspects of these particles has lagged far behind their fast growing application. objectives the cu...

The diagnosis of malignant brain gliomas is largely based on magnetic resonance imaging (MRI) with contrast agents. In recent years, nano-sized contrast agents have been developed for improved MRI diagnosis. In this study, oleylamine-coated Fe3O4 magnetic nanoparticles (OAM-MNPs) were synthesized with thermal decomposition method and encapsulated in novel amphiphilic poly(aminoethyl ethylene ph...

magnetic nanoparticles are the good choice for using in mri as the contrast agent. iron oxide particles such as magnetite (fe3o4) or its oxidized form maghemite (γ-fe2o3) are the most commonly employed in biomedical applications. in this study, we synthesized and optimized the preparation of chitosan manganese-ferrite nanoparticles (cmn-fe nps) and evaluated its ability for the mice macrophage ...

background: among different pollutants released into the environment, dyes are considered as one of the most dangerous contaminants. in recent years, magnetic nanomaterials have attracted much attention for their dye removal capacity. the aim of this study was to explore the adsorption kinetics of an anionic dye (reactive orange 13 (ro)) by nife2o4 nanoparticles (nife2o4 nps) under various cond...

Nanoparticles (NPs) show new characteristics compared to the corresponding bulk material. These nanoscale properties make them interesting for various applications in biomedicine and life sciences. One field of application is the use of magnetic NPs to support regeneration in the nervous system. Drug delivery requires a functionalization of NPs with bio-functional molecules. In our study, we fu...

This article reports the development of biodegradable photoluminescent polymer (BPLP)-based nanoparticles (NPs) incorporating either magnetic nanoparticles (BPLP-MNPs) or gadopentate dimeglumine (BPLP-Gd NPs), for cancer diagnosis and treatment. The aim of the study is to compare these nanoparticles in terms of their surface properties, fluorescence intensities, MR imaging capabilities, and in ...