In Ontario, Canada, beta-thalassemia is easily detected through measurement of hemoglobin A2, but most laboratories do not do exhaustive DNA investigations for alpha-thalassemia. Therefore, the prevalence of thalassemia in microcytic samples for hemoglobinopathy investigation in Ontario is unknown. To address this, we performed a prospective cohort study in which samples referred for hemoglobin...

BACKGROUND The Gγ-158(C→T) polymorphism plays important function in the clinical variability of HbE/β-thalassemia. There is little known about Gγ-158(C→T) polymorphism in HbE/β-thalassemia major in Southern China. This study aimed to explore the association between HbE/β-thalassemia major and this polymorphism in Southern China. METHODS AND RESULTS The frequency of the Gγ-158(C→T) polymorphis...

Abstract One of the most prevalent genetic diseases in world is beta thalassemia. Hemoglobin synthesis decreased by blood condition Patients with thalassemia exhibit a range bone problems, including as spinal deformities, osteopenia and osteoporosis, well growth failure. This study’s main goal was to evaluate gait balance Albanian β-thalassemia patients. In this study, 18 participants aged 17 2...

Thalassemia is a group of inherited blood disorders due to the reduction or absence globin chain synthesis which can cause hemolytic anemia. β-thalassemia major severe type thalassemia, in patients require lifelong transfusions for survival. Extravascular hemolysis on spleen results splenomegaly, meanwhile, extramedullary hematopoiesis causing hypersplenism develop beta-thalassemia patients. Hy...

Beta thalassemia (β thalassemia) is a group of inherited blood disorders. Case report A 17-year old boy accompanied by medical support staff visited our Department for preventive and pediatric dentistry within the University Dental Center Ss.Pantelejmon in Skopje, due to dental pain which comes from first molar tooth(36) low jaw left side.