T ^ H E METHOD of duct management that X is optimal for pancreatic (P) transplantation (Tx) continues to be a major controversy. An analysis of the Pancreas Transplant Registry shows no differences in results for the three major duct management techniques, polymer injection, enteric drainage, and urinary tract diversion (UTD). All techniques have advantages and disadvantages. Duct injection is ...

Intrahepatic bile duct strictures are a serious complication after orthotopic liver transplantation (OLT). We examined the role of endogenous bile salt toxicity in the pathogenesis of bile duct injury after OLT. Livers from wild-type mice and mice heterozygous for disruption of the multidrug resistance 2 Mdr2 gene (Mdr2+/-) were transplanted into wild-type recipient mice. Mdr2+/- mice secrete o...

BACKGROUND Major bile duct injury is an important therapeutic problem that can be associated with simultaneous injury to the hepatic artery. Limited information exists regarding the course of patients who have combined bile duct and arterial injuries. OBJECTIVE To compare the management and outcome of isolated bile duct injuries with bile duct and hepatic artery injuries. PATIENTS AND METHO...

persistent mullerian duct syndrome in a 71-year-old man, case report h. salehi md , m.r. vatani baf md received:27/06/06 sent for revision: 11/10/06 received revised manuscript: 07/02/07 accepted: 12/02/07 background and objective: normal sexual differentiation occurs in the 6th embryonic week and in a normal embryonic life. both wolffian and mullerian ducts are present until the onset of sexua...

STUDY DESIGN Multicenter retrospective case series. OBJECTIVE To determine the rate of thoracic duct injury during cervical spine operations. METHODS A retrospective case series study was conducted among 21 high-volume surgical centers to identify instances of thoracic duct injury during anterior cervical spine surgery. Staff at each center abstracted data for each identified case into case...

BACKGROUND AND AIMS Acute necrotizing pancreatitis (ANP) can affect main pancreatic duct (MPD) as well as parenchyma. However, the incidence and outcomes of MPD disruption has not been well studied in the setting of ANP. METHODS This retrospective study investigated 84 of 465 patients with ANP who underwent magnetic resonance cholangiopancreatography and/or endoscopic retrograde cholangiopanc...

Presenter: Sergio Riveros MD | Pontificia Universidad Católica de Chile Background: Living donor liver transplantation (LDLT) is a complex therapeutic alternative that requires specialized multidisciplinary team with the capacity to resolve complications. The number of anastomosed ducts has an impact on rate postoperative biliary complications, but literature still scarce. objective this study ...

BACKGROUND/AIMS Approximately 5% to 10% of common bile duct (CBD) stones are difficult to remove by conventional endoscopic methods. Percutaneous transhepatic cholangioscopic lithotomy (PTCSL) can be an alternative method for this condition, but is not well established yet. The aim of this study was to evaluate the clinical efficacy and safety of PTCSL for removal of difficult CBD stones. MET...

The mineralocorticoid aldosterone is a major regulator of sodium transport in target epithelia and contributes to the control of blood pressure and cardiac function. It specifically functions to increase renal absorption of sodium from tubular fluid via regulation of the alpha subunit of the epithelial sodium channel (alphaENaC). We previously used microarray technology to identify the immediat...

the function of genes coding for transmembrane ion channels and transporters expressed in specialised cells of the cochlea and vestibule. We have characterised the expression patterns of zebrafish genes orthologous to those involved in endolymph production in the mammal and find that the major site of expression of these genes in the developing ear is in the epithelial projections that form the...