نتایج جستجو برای: major thalassemia
تعداد نتایج: 636036 فیلتر نتایج به سال:
OBJECTIVE Growth retardation in children with b-thalassemia major is multifactorial. Some etiologies described for this condition are hemochromatosis, disturbed growth hormone (GH) / insulin growth factor-1 (IGF-1) axis, undernutrition and hypermetabolism. It has also been proven that growth retardation is present in b-thalassemia major children despite regular transfusion and chelation. Our ai...
Thalassemia intermedia encompasses a wide clinical spectrum of beta-thalassemia phenotypes. Some thalassemia intermedia patients are asymptomatic until adult life, whereas others are symptomatic from as young as 2 years of age. A number of clinical complications commonly associated with thalassemia intermedia are rarely seen in thalassemia major, including extramedullary hematopoiesis, leg ulce...
Thalassemia is a hereditary condition that affects the formation of globin chains. Beta thalassemia characterized by either total loss manufacture (β-thalassemia major) or partial minor). This type inherited anemias found in Mediterranean and Southeast Asian communities. Objective: Assessment parents' knowledge regarding home health care management related to children with β-Thalassemia Major. ...
BACKGROUND Major Thalassemia is an autosomal recessive disease with complications, mortality and serious pathology. Today, the life expectancy of patients with major thalassemia has increased along with therapeutic advances. Therefore, they need lifelong care, and caring for them would incur many costs. Being aware of the patients' costs can be effective for controlling and managing the costs a...
Background: Hydroxyurea (HU) is a well known chemotherapeutic agent that has been used largely for various myeloproliferative diseases over the past 20 years. In β-thalassemia, the effect of HU is much less clear and remains controversial. This study was undertaken to describe the hematologic and clinical responses of thalassemia major and intermediate patients to HU treatment during 2 years. M...
background: heart disease is the main cause of mortality and morbidity in patients with beta thalassemia, rendering its early diagnosis vital. we studied and compared echocardiographic findings in patients with beta thalassemia major, patients with beta thalassemia intermedia, and a control group. methods: eighty asymptomatic patients with thalassemia major and 22 asymptomatic cases with thalas...
thalassemia major is a genetic blood disorder that is detected by the symptoms of chronic and severe anemia, failure to thrive, an enlarged liver and spleen, bone deformities particularlya deformed face and bulging forehead. due to changes in physical appearance, the disease can influence on other aspects of the patient's life, so the disease could strongly impact on the mental health of t...
background: since the reduction of mental health in patients with thalassemia may affect the quality of life and cause dysfunction in various dimensions, so the assessment of this disorder is necessary to choose the appropriate treatment. therefore, the aim of this study was to investigate the mental health and quality of life in patients with thalassemia major. methods: in this cross-sectional...
background: β-thalassemia is an autosomal hemoglobinopathy with inconsistent universal distribution. among patients with thalassemia diverse non-siderotic complications distinctly influence the attribute of life, including zinc deficiency due to varied etiologies. the objective of the present study was to determine zinc levels in patients with β-thalassemia major and its correlation with matern...
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