herein we describe a case of intraocular melanoma in a17-year old leukemic patient.   the history, histological findings of the enucleated eye, blood and bone marrow of the patient were investigated. the enucleated eye contained epitheloid cell type melanoma instead of leukemic cell infiltration.  we conclude that intraocular malignant melanoma can occur in acute lymphoblastic leukemia.

purpose : choroidal melanoma is the most common primary ocular malignancy among the adult population. authors investigated the clinical findings, histopathologic features, types of retinal detachment and the precise anatomic origin of enucleated eyes for primary ocular malignant melanoma in shiraz university of medical sciences (sums) hospitals between 1990 and 2005. methods : this was a cross ...

Malignant melanoma (MSA) is a cancer of pigmented cells called melanocytes. Cutaneous malignant melanoma may occur in the nail bed or on the foot pads. Melanomas that arise from the haired skin of the body, legs, or eyelids are usually benign but in rare cases can exhibit aggressive behavior similar to those of the nail bed, foot pads or mouth. Malignant melanoma can be a very aggressive cancer...

vitiligo is a disease that results in depigmented areas in the skin. it may develop at any age but the average age at onset is 20 years. association of vitiligo and melanoma has been commonly reported, but malignancies other than melanoma have been rarely associated with vitiligo. we report a 73‑year‑old patient with new onset vitiligo who developed esophageal adenocarcinoma in the following ye...

introduction: the incidence of malignant melanoma is increasing at a rate greater than any other human cancer. although melanoma accounts for only 4 percent of all dermatologic cancers, it is responsible for 80 percent of deaths from skin cancer; only 14 percent of patients with metastatic melanoma survive for five years. the optimal therapy varies with the stage of the disease. surgical excisi...

Pigmented Bowens disease is an in situ squamous cell carcinoma, which is seldom reported in white patients. Herein we report a 20-year-old woman with type III skin, who had this lesion on the fourth finger of her right hand, similar to superficial malignant melanoma, clinically. Although dermoscopic evaluation could be helpful, correct diagnosis of non-melanotic origin is done by histological e...

Background and Objective: The primary goal of this study is to develop a rigorous understanding ofthe correlation between COX-2 expression and malignant melanoma prognostic factors. Material and Methods: In this cross-sectional study, we analyzed 60 cases of cutaneous malignant melanoma. The related stained slides were reviewed by two pathologists. The re...

conclusions cmm in yazd is a low-incidence skin tumor that shows a relatively fixed incidence between 1988 and 2008, higher incidences of cmm were found in sun-exposed areas (especially head and neck areas), with more incidence in men. skin cancers and cmm incidence in iran is lower than western countries, most probably due to geographical zone, genetic factors, skin type, society-related custo...

Malignant Peripheral Nerve Sheath Tumor (MPNST) is a rare soft tissue sarcoma that can occur in superficial locations. Histologically it is categorized into two variants: a conventional/spindled and an epithelioid variant. The latter one is very rare and can be confused histologically with malignant melanoma as it is diffusely positive for S100-protein. Herein we present a case that was initial...

Background & Objective: This study was designed for the first time for the detection of mutant BRAF V600E and its correlation with clinicophathologic features in a sample of Iranian patients with pathologically proved pigmented skin neoplasms.Methods: 82 paraffin-embedded blocks, including melanocytic nevi, malignant melanoma, Basel cell carcinoma, and sq...