Meningiomas, derived from arachnoid cap cells, are the most common intracranial tumor. High-grade meningiomas, as well as those located at the skull base or near venous sinuses, frequently recur and are challenging to manage. Next-generation sequencing is identifying novel pharmacologic targets in meningiomas to complement surgery and radiation. However, due to the lack of in vitro models, the ...

Brain tumor like meningioma which can be detailed classified in malignant type the incidents rates are only 1.7%. This of cases have very poor prognosis. The option for this patient was palliative care and hopefully shown faith on homoeopathy as last option. Some well proven clinically verified pathological medicines worked miraculously proved its efficacy fatal disease.

Aim. To evaluate the frequency of atypical and malignant meningiomas and analyze recurrence rate; to study the morbidity and mortality of these tumors compared to benign meningiomas. Methods. During 1992-2007, 16 patients with malignant and 16 patients with atypical meningioma were operated in Neurosurgery Department of Thessaloniki's Papanikolaou Hospital. We analyzed tumor histology, location...

mone deficiencies). Radiation therapy greatly increases the lifelong risk of secondary malignant neoplasms (glioblastoma multiforme, malignant astrocytoma, meningioma, bone and soft-tissue sarcoma, and malignant melanoma) in children with TRB who are already predisposed to secondary cancers owing to their germline RB1 mutations. Treatment of TRB using the Toronto Protocol and intrathecal topote...

Meningioma is a common pathology in the central nervous system (CNS). It arises from the arachnoid cap cells of the arachnoid villi in the meninges, which envelop the brain and spinal cord. Therefore, a meningioma can occur anywhere from the vertex to the spine. It is often named according to its anatomical location. For example, a meningioma abutting the sphenoid bone between the frontal and t...

Early and delayed 201Tl SPECT studies were performed on 13 patients with intracranial meningiomas, which were classified in three groups according to their histological types: meningothelial (n = 7); transitional and fibroblastic (n = 3); and malignant types (n = 3). The early uptake indices (UI, ratios of average counts/pixel in the lesion to those of the contralateral area on early images) we...

PURPOSE This study explores whether meningioma expresses epidermal growth factor receptor (EGFR) and determines if there is a correlation between the WHO grade of this tumor and the degree of EGFR expression. METHODS Following institutional review board approval, 113 meningioma specimens from 89 patients were chosen. Of these, 85 were used for final analysis. After a blinded review, immunohis...

Background: Meningiomas are slow-growing neoplasms, accounting for 20% of all primary intracranial neoplasms and 25% intraspinal tumors. Atypical anaplastic meningiomas infrequent, representing fewer than 5% meningiomas. Unusually, they can show aggressive behavior, extracranial metastases extremely rare, approximately 0.1% reported cases. Case Description: Fifty-six-year-old male patient diagn...