نتایج جستجو برای: mammea africana nephroprotective antioxidant kidney

تعداد نتایج: 313749  

Journal: :African health sciences 2015
Madinah Naggayi Nozmo Mukiibi Ezekiel Iliya

BACKGROUND Oxidative stress plays a crucial role in the development of drug induced nephrotoxicity. The study aimed to determine the nephroprotective and ameliorative effects of Carica papaya seed extract in paracetamol-induced nephrotoxicity in rats. OBJECTIVES To carry out phytochemical screening of Carica papaya, measure serum urea, creatinine and uric acid and describe the histopathologic...

2016
Hilal Bektas Uysal Bekir Dagli Mustafa Yilmaz Fadime Kahyaoglu Alparslan Gökçimen Imran Kurt Omurlu Buket Demirci Adnan Menderes

Acetaminophen (paracetamol, APAP) has a worldwide usage. Nevertheless, overdosing may induce severe toxicity. Dexpanthenol (DXP) is the alcohol provitamin form of vitamin B5 with antiinflammatory and antioxidant efficacy. In the present study, the biochemical and histological protective effects of DXP against acetaminophen-induced oxidative hepatorenal damage were examined. Rats were divided in...

Journal: :jundishapur journal of natural pharmaceutical products 0
mojtaba kalantar student research committee, ahvaz jundishapur university of medical sciences, ahvaz, ir iran; shoushtar faculty of medical sceinces, shoushtar, ir iran mehdi goudarzi student research committee, ahvaz jundishapur university of medical sciences, ahvaz, ir iran; medicinal plant research center, ahvaz jundishapur university of medical sciences, ahvaz, ir iran; department of pharmacology and toxicology, school of pharmacy, ahvaz jundishapur university of medical sciences, ahvaz, ir iran. tel: +98-6133738378 mohammad javad khodayar department of toxicology, school of pharmacy, ahvaz jundishapur university of medical sciences, ahvaz, ir iran javad babaei department of health, valiasr hospital research center, rescue and treatment of police force, tehran, ir iran hossein foruozandeh department of toxicology, school of pharmacy, ahvaz jundishapur university of medical sciences, ahvaz, ir iran nima bakhtiari department of toxicology, school of pharmacy, ahvaz jundishapur university of medical sciences, ahvaz, ir iran

background cyclophosphamide (cp) is one of the most popular alkylating anticancer drugs despite its toxic side effects, including nephrotoxicity, hematotoxicity, mutagenicity, and immunotoxicity. capparis spinosa is a multipurpose plant that contains a number of chemically active and diverse secondary metabolites, particularly flavonoids. rutin and quercetin are two major flavonoids in the cape...

2007
Surat Laphookhieo John Keith Syers Akkharawit Kanjana-Opas Chanita Ponglimanont Chatchanok Karalai

Uma cumarina inédita, mammea E/BB ciclo D (1), juntamente com cinco compostos conhecidos, mammea E/BA ciclo D (2), suragina C (3), terapina B (4), 1,7-dihidroxixantona (5) e 1-hidróxi-5-metoxyxantona (6), foram isolados de sementes de Mammea siamensis. Suas estruturas foram caracterizadas usando dados de RMN 1D e 2D. Suragina C e terapina B mostraram atividade citotóxica contra adenocarcinoma d...

2012
Ahmed E. Abdel Moneim Kamal M. El-Deib

Physalis peruviana (physalis) has long held a place in folk medicine in the tropical countries where it grows. Here, the aim of this study was to evaluate the potential nephroprotective impact of physalis extract against carbon tetrachloride (CCl4)-induced kidney injury and to explore the possible mechanisms by which this plant exerts its beneficial effects. Rats were randomly divided into equa...

Jessy Elizabeth Mathew, Keloth Kaitheri Srinivasan Kerryn Joseph A.D’Silva Nimmy Kumar, Richard Lobo,

Objective(s):To evaluate the effect of Graptophyllum pictum on lipid peroxidation and tissue antioxidant enzymes in liver and kidney of gentamicin induced nephrotoxic rats. Materials and Methods: Animals were grouped into 6: Group 1 received gum acacia, Group 2 received G. pictum ethanol extract (300 mg/kg), Group 3 received gentamicin, Groups 4, 5, 6 received gentamicin along with G. pictum a...

2012
MOHANA LAKSHMI

Medicinal plants may serve as a vital source of potentially useful new compounds for the development of effective therapy to combat a variety of kidney problems. Many herbs have been proven to be effectual as nephroprotective agents while many more are claimed to be nephroprotective but there is lack of any such scientific evidence to support such claims. Developing a satisfactory herbal therap...

Journal: :Acta poloniae pharmaceutica 2012
Akbar Hajizadeh Moghaddam Seyed Mohammad Nabavi Seyed Fazel Nabavi Rata Bigdellou Sakineh Mohammadzadeh Mohammad Ali Ebrahimzadeh

This study was conducted to quantitatively evaluate the antioxidant, antihemolytic and nephroprotective effects of Diospyros lotus seeds extract in experimental in vitro and in vivo models. Antioxidant potential of Diospvyos lotus seeds extract was examined by employing seven in vito models i.e., DPPH, nitric oxide and hydrogen peroxide radicals scavenging activity, iron ion chelating, reducing...

MM Zangeneh ,

Background: Certainly, the trend in the treatment of diabetes by ethnomedicinal plants which have fewer side effects than chemical drugs has enhanced. Anthemis odontostephana Boiss has been recently known as an antioxidant, antiflammatory, and antimicrobial agent. Objective: hematoprotective and nephroprotective properties of Anthemis odontostephana Boiss ethanolic extract (AOEE) on diabetic m...

2015
Peter Masoko David M. Makgapeetja

BACKGROUND Olea africana leaves are used by Bapedi people to treat different ailments. The use of these leaves is not validated, therefore the aim of this study is to validate antimicrobial properties of this plant. METHODS The ground leaves were extracted using solvents of varying polarity (hexane, chloroform, dichloromethane (DCM), ethyl acetate, acetone, ethanol, methanol, butanol and wate...

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