BACKGROUND AND OBJECTIVES It remains controversial whether splenic and nodal marginal zone B cells, monocytoid -, and epithelial-associated B cells represent separate B-cell subsets or just variants of the same population. To clarify this issue we studied the antigen profile and topographical distribution of these cell types. DESIGN AND METHODS We studied samples of toxoplasmic lymphadenopath...

A concept known as ‘marginal gains’, an approach to performance improvement in elite sport came to prominence during the London 2012 Olympics when Team GB cycling won a record eight gold medals. Since National Lottery funding was awarded in 1997 to develop British cycling, the ethos of making aggregated small gains in many areas to improve overall performance has been central to its success. Th...

A traffic simulation and assignment model is used to compute the social costs of congestion in five English towns, together with potential road charges. The social costs of congestion are measured by the deadweight loss and computed as the area between the marginal social cost and inverse demand curves between the actual and efficient levels of traffic. Potential road charges are computed as th...

Introduction With vast investment and employment opportunities, India's urban areas have already become the engine of the country's development, drawing in everyone from the global real estate firm to the displaced marginal farmer. The World Bank estimates that urban areas currently house 32 percent of India's population of 1.2 billion, the highest proportion in Indian history.

Dendritic cells (DCs) are strategically positioned to take up antigens and initiate adaptive immunity. One DC subset expresses CD8alphaalpha in mice and is specialized to capture dying cells and process antigens for MHC class I "cross-presentation." Because CD8(+) DCs also express DEC205/CD205, which is localized to splenic T cell regions, it is thought that CD8(+) DCs also are restricted to T ...

background and aim: an important criterion for success assessment of implant-supported prostheses is marginal fit. vertical and horizontal discrepancy can result in loosening of the prosthetic screw, crestal bone resorption, peri-implantitis and loss of osseointegration. despite careful attention to waxing, investing, and casting, marginal discrepancies are inevitable. the aim of this study was...

objective: this experimental in vitro study compared marginal adaptation of indirect composite, glass-ceramic inlays and direct composite. materials and methods: seventy-five recently extracted human molars were randomly divided into three groups (n=25) and mesio-occluso-distal cavities with the same dimensions were prepared in the teeth. indirect composite and glass-ceramic inlays were fabrica...

Oral rehabilitation of endodontically treated roots is inherently difficult, and the functional loads result in extremely complex structural responses of the oral tissues. The objective of this study was to evaluate, by finite element analysis, stresses induced in an endodontically treated maxillary central incisor that was restored with a cast metallic post and core system and a overlying cera...

Objectives. The aim is to evaluate the survival and success rates, as well as the marginal bone loss (MBL) and periodontal indexes of zirconia implants positioned in the esthetic jaw areas. Materials and Method. 13 patients were selected and 20 one-piece zirconia implants were used for the rehabilitation of single tooth or partially edentulous ridge in the esthetic jaw areas. Six months after s...

This paper considers some fundamental questions concerning marginally trapped surfaces, or apparent horizons, in Cauchy data sets for the Einstein equation. An area estimate for outermost marginally trapped surfaces is proved. The proof makes use of an existence result for marginal surfaces, in the presence of barriers, curvature estimates, together with a novel surgery construction for margina...