Red blood cell transfusions are used to treat hemorrhage and to improve oxygen delivery to tissues. Transfusion of red blood cells should be based on the patient's clinical condition. Indications for transfusion include symptomatic anemia (causing shortness of breath, dizziness, congestive heart failure, and decreased exercise tolerance), acute sickle cell crisis, and acute blood loss of more t...

background: malaria is the most important transfusion-transmitted infection (tti) in worldwide after viral hepatitis and human immunodeficiency virus (hiv) infection. the main objective of the present study was to review and evaluate the transmission of malaria via blood transfusion in iran. methods : a literature search was done without time limitation in the electronic databases as follows: p...

Hemorrhagic shock is a leading cause of death in trauma patients. Surgical control of bleeding and fluid resuscitation with both crystalloid and blood products remain the mainstay of therapy for injured patients with bleeding. However, there has been a recent re-evaluation of transfusion practice. Both the fear of transmissible disease and the costs of transfusing blood products have led to inc...

background: reservation of blood leads to blood wastage if the blood is not transfused. therefore, in some centers only blood type and screen are evaluated. in this study, the efficacy of a blood crossmatch-to-transfusion ratio was measured and then compared with the standard levels. methods: this prospective study was conducted during one year in a university hospital. during this period, 398 ...

transfusion of blood products from an infected person with aids, is meant to infect recipient. blood products such as whole blood, red blood cells, platelets, plasma, frozen blood precipitate, factor viii, factor ix, can be infected with hiv. transmissions from blood factors can be seen in plasma from thousands of donors that were collected in a container and were used to treat hemophilia. bloo...

HYPOTHESIS Survival following massive transfusion in patients who have undergone trauma has improved during the past 10 years. DESIGN Retrospective cohort study. SETTING Academic level I trauma center in an urban community. PATIENTS All patients who underwent trauma and who received greater than 50 U of packed red blood cells or whole blood in the 48 hours following admission to the emerg...

BACKGROUND Few studies have examined the impact of balanced resuscitation in pediatric trauma patients requiring massive transfusions. Adult data may not be generalizable to children. METHODS Retrospective analysis assessed patients seen at a level I trauma center between 2003 and 2010 aged ≤18 years requiring massive packed red blood cell (PRBC) transfusion, defined as transfusion of ≥50% to...