This study was designed to test the hypothesis that the medullary lateral tegmental field (LTF) is an important synaptic relay in the baroreceptor reflex pathway controlling sympathetic nerve discharge (SND) of urethan-anesthetized cats. We determined the effects of blockade of excitatory amino acid-mediated neurotransmission in the LTF on three indexes of baroreceptor reflex function: cardiac-...

Abnormal atrial refractoriness was examined as a cause of atrial fibrillation/flutter (AFF) in patients with bradycardia. Refractory periods at three disparate right atrial sites were compared in 17 patients with sinus node dysfunction (SND) and 16 controls. Atrial pacing shortened refractory periods, but failed to decrease dispersion of refractoriness significantly. During sinus rhythm, durati...

BACKGROUND Patients with sinus node dysfunction (SND) have increased risk of atrial tachyarrhythmias, including atrial fibrillation (AF). To date, treatment patterns and outcomes of patients with SND and AF have not been well described. HYPOTHESIS Patients with SND and AF have higher risk of adverse cardiovascular outcomes. METHODS Sinus node dysfunction was defined clinically, based on tre...

Sympathetic nerve discharge (SND) responses to hyperthermia are attenuated in aged rats without heart failure (HF) and in young HF (Y(HF)) rats, demonstrating that individually aging and HF alter SND regulation. However, the combined effects of aging and HF on SND regulation to heat stress are unknown, despite the high prevalence of HF in aged individuals. We hypothesized that SND responses to ...

A novel nanofiltration membrane bioreactor (NF-MBR) was constructed by integrating a loosely structured hollow fiber into an aerobic activated sludge system. In order to verify the feasibility of loose NF bioreactor, parallel experiments conventional ultrafiltration (UF-MBR) and NF-MBR were conducted investigate process performances, fouling characteristics. The showed relatively high permeabil...

The performance of combined Fenton oxidation and membrane bioreactor (MBR) process for the advanced treatment of an effluent from an integrated dyeing wastewater treatment plant was evaluated. The experimental results revealed that under the optimum Fenton oxidation conditions (initial pH 5, H2O2 dosage 17 mmol/L, and Fe2+ 1.7 mmol/L) the average total organic carbon (TOC) and color removal rat...

With stringent wastewater discharge limits on nitrogen and phosphorus, membrane bioreactor (MBR) technology is gaining popularity for advanced wastewater treatment due to higher effluent quality and smaller footprint. However, higher energy intensity required for MBR plants and increased operational costs for nutrient removal limit wide application of the MBR technology. Conventional nitrogen r...

The t(14,18) chromosomal translocation that occurs in human follicular lymphoma constitutively activates the BCL2 gene and disrupts control of apoptosis. Interestingly, 70% of the t(14,18) translocations are confined to three 15-bp clusters positioned within a 150-bp region (major breakpoint region or [MBR]) in the untranslated portion of terminal exon 3. We analyzed DNA-protein interactions in...

Oily wastewater is generated from various sources within the petrochemical industry, including extraction, refining and processing, storage, transportation. Over years, large volumes of oily this industry have made their way into environment, negatively affecting human health, economy. The raw waters can differ significantly complex features, making them difficult to treat. Membrane bioreactors...