Monocyte-derived macrophages (MDM) are widely distributed in all tissues and organs, including the central nervous system, where they represent the main part of HIV-infected cells. In contrast to activated CD4(+) T lymphocytes, MDM are resistant to cytopathic effects and survive HIV infection for a long period of time. The molecular mechanisms of how HIV is able to persist in macrophages are no...

Lung macrophages are an important defence against respiratory viral infection and recent work has demonstrated that influenza-induced macrophage PDL1 expression in the murine lung leads to rapid modulation of CD8+ T cell responses via the PD1 receptor. This PD1/PDL1 pathway may downregulate acute inflammatory responses to prevent tissue damage. The aim of this study was to investigate the mecha...

The original topological Aharonov-Casher (AC) effect is due to the interaction of the anomalous magnetic dipole moment (MDM) with certain configurations of electric field. Naively one would not expect an AC effect for a scalar particle for which no anomalous MDM can be defined in the usual sense. In this letter we study the AC effect in supersymmetric systems. In this framework there is the pos...

 Abstract—Mode division multiplexing (MDM) has the potential of increasing the capacity of optical fiber transmission system. However, primary impaired factor mode-dependent loss (MDL) poses fundamental performance limitations. Recently MIMO space time coding technique has provided a potential solution to mitigate the MDL and hence started receiving considerable interests. In this paper, ortho...

Neuronal damage in human immunodeficiency virus type 1 (HIV-1) infection in the brain is thought to occur at least in part through NMDA receptor (NMDAR) excitation initiated by soluble neurotoxins from HIV-infected brain macrophages. Furthermore, brain regions enriched in NMDAR-2A (NR2A) and NMDAR-2B (NR2B) subunits, such as the hippocampus, are particularly vulnerable. Using cultured rat hippo...

Magnesium (Mg) has drawn increasing attention as a tissue engineering material. However, there have been very few studies of laser-melted Mg-Zn alloys. In this study, four binary Mg-xZn (x = 2, 4, 6 and 8 wt. %) alloys were fabricated by laser melting. The influence of zinc (Zn) content and technique on the degradation behavior and mechanical properties of Mg were discussed. Results revealed th...

The alpine wetlands in the Qinghai-Tibetan Plateau have degraded recent decades. However, response of soil food web to degradation is still unclear. Four habitats including a wet meadow (WM), grassland (GM), moderately (MDM) and severely (SDM) (sandy meadows) were selected along degrees degradation. macrofaunal biomass environmental factors vegetation investigated. community increased significa...

Purpose To develop a particle transport code to compute w-values and stopping power of swift ions in liquid water gases interest for reference dosimetry hadrontherapy. analyze the relevance inelastic post-collisional processes considered. Methods The Monte Carlo MDM was extended case ion impact on (MDM-Ion). Relativistic corrections cross sections Auger emission were effects introducing differe...