During heart valve remodeling, and in many disease states, valvular interstitial cells (VICs) shift to an activated myofibroblast phenotype which is characterized by enhanced synthetic and contractile activity. Pronounced alpha smooth muscle actin (αSMA)containing stress fibers, the hallmark of activated myofibroblasts, are also observed when VICs are placed under tension due to altered mechani...

Regarding the activation of chemical reactions, today’s chemist is used to thinking in terms of thermochemistry, electrochemistry, and photochemistry, which is reflected in the organization and content of the standard physical chemistry textbooks. The fourth way of chemical activation, mechanochemistry, is usually less well-known. The purpose of the present review is to give a survey of the cla...

The intensification of the thiourea leaching of gold from goldsmith's waste (Košice, Slovakia) using mechanical activation as the pretreatment step. The leaching of “as-received“ sample in an acid thiourea solution resulted in 77 % Au dissolution, after mechanical activation 98 % of the gold was leached during 120 min. The activation was performed in an attritor using variable milling times. Th...

in this study, the adsorption of hexavalent chromium and zinc ions from the solution is investigated by raw red mud and mechanical-chemical activated red mud along with the possibility of selective reclamation of these ions from the solution. the mechanical-chemical activation of red mud was done by employing high-energy milling and subsequent acid treatment with hno3. raw red mud (rrm) and mec...

BACKGROUND AND OBJECTIVES Mechanical stimulation and hormones act via interconnected signaling pathways to influence the function of bone cells. Estrogen receptor (ER) and β-catenin play important role in bone formation and have implicated in mechanotransduction in bone cells. To investigate the interaction between mechanotransduction and estrogenic signaling in mesenchymal stem cells (MSCs), t...

Abstract: has been investigated. It has been shown that the mechanism of leaching reaction is diffusion through the product layerand does not undergo any change as a result of mechanical activation in a wide range of experimental conditions.Leaching rate is strongly influenced by milling intensity and the effect of ball to powder mass ratio is stronger thanmilling time. Curve fitting of experim...

Tidball, James G. Mechanical signal transduction in skeletal muscle growth and adaptation. J Appl Physiol 98: 1900 –1908, 2005; doi:10.1152/japplphysiol. 01178.2004.—The adaptability of skeletal muscle to changes in the mechanical environment has been well characterized at the tissue and system levels, but the mechanisms through which mechanical signals are transduced to chemical signals that i...

The article presents the results of study filler particles activation mechanism in production composite polymeric materials modified by mechanical activation. studies were conducted simulated conditions motion taking into account trajectory during milling progressive-rotational units using analytical expression velocity distribution each particle material.