Intestinal obstruction complete or incomplete has been found commonly in patients with cystic fibrosis all age groups variable presentation. Prevalence of intestinal children is 7-8%. Neonates present meconium ileus due to inspissated and obstruction. This case demonstrates similar presentation a pediatric patient. A six day old male patient presented the surgery department abdominal distention...

The clinical symptoms of a cohort of cystic fibrosis patients were related to their genotypes using RFLPs shown with MspI and the closely linked DNA marker MP6d-9. In the majority of CF chromosomes, the restriction site for MspI was present, and the genotype 2/2 was found most often in patients who were severely affected by the disease. The genotype 1/2 was significantly over-represented in pat...

rate in terms of the amount of sweat produced and the virtual absence of failures. On the first day of life the average level of sweat sodium was decidedly higher than on the second and subsequent days, with an appreciable number of day 1 results exceeding the level of 70 mEq/1., generally accepted as the upper limit of normal. In one case the level was as high as 138 mEq/1. All 5 out of the 6 ...

Abnormal fucosylation of cystic fibrosis mucin was previously shown using peroxidase conjugated lectins on ileal tissue sections. These abnormally fucosylated glycoproteins were investigated further using monoclonal antibodies to fucosyl oligosaccharides based on type 1 and type 2 blood group precursor chains. The results of this study, using monoclonal antibodies to blood group glycoproteins i...

OBJECTIVE To assess the effectiveness of a two tier neonatal screening strategy for cystic fibrosis, which combines estimation of immunoreactive trypsinogen followed by direct gene analysis in dried blood spot samples collected at age 5 days. DESIGN Prospective study of two tier screening strategy. The first tier of testing immunoreactive trypsinogen concentration was measured in dried blood ...

an histologically normal liver at necropsy. The two survivors were jaundiced for 6 months and 5 weeks respectively, before making a clinical recovery, and in both liver biopsy at the height of the jaundice showed bile stasis. Meconium ileus was present in half of all recorded cases of cystic fibrosis with prolonged neonatal jaundice. Jaundice is probably due to extrahepatic biliary obstruction ...

BACKGROUND The significance of meconium plug syndrome is dependent on the underlying diagnosis. The incidence of pathologic finding, particularly Hirschsprung's disease, contributing to the presence of these plugs, has been debated. However, there are little recent data in the literature. Therefore, we reviewed our experience with meconium plugs as a cause of abdominal distension to evaluate th...