Melasma is a dysregulation of the homeostatic mechanisms that control skin pigmentation and excess pigment is produced. Traditional treatment approaches with topical medications and chemical peels are commonly used but due to the refractory and recurrent nature of melasma, patients often seek alternative treatment strategies such as laser and light therapy. Several types of laser and light ther...

Known as the “pregnancy mask,” over six million Americans are impacted by hormonally induced melasma every year, making it one of the most common skin concerns in the United States. Affecting female patients in 90% of cases, melasma appears in large, dense patches of pigmentation, usually on the malar, mandibular and centrofacial areas of the face. Although melasma can affect anyone, it tends t...

Melasma is a common dermatosis that involves changes in normal skin pigmentation, resulting from the hyperactivity of epidermal melanocytes. The consequent hyperpigmentation is mostly induced by ultraviolet radiation. Clinically, melasma is characterized by light to dark brown macules that usually occur on the face, although they can also affect the cervical and anterior thoracic regions and up...

Melasma is a common hypermelanotic disorder affecting the facial area which has a considerable psychological impact on the patient. Managing melasma is a difficult challenge that requires long-term treatment with a number of topical agents, such as rucinol and sophora-alpha. Aims. We aim to compare the combined treatment of skin needling and depigmenting serum with that using depigmenting serum...

Background: Melasma is a common disorder of acquired hyperpigmentation affecting millions people worldwide, predominantly women. Despite the incidence, there are numerous hyperpigmentary conditions which may clinically resemble melasma. The differential diagnosis melasma therefore wide and prove to be diagnostic challenge for clinicians. This can delay appropriate treatment, adversely impacting...

Copper Bromide Laser vs Triple-Combination Cream for the Treatment ofMelasma: A Randomized Clinical Trial Recent studies have suggested the potential effectiveness of targeting the vascular component of melasma.1-4 The copper bromide laser (Dual Yellow;Norseld) is a laserwith a concomitant-outputdual-wavelength light source comprising90%yellowlightat578nm,whichtargetsvascular lesions,and10% gre...

We reported two cases of clinically typical melasma presenting with unusual histopathologic findings. In one case, the epidermal melanocytes were markedly increased in number and protruded into the dermis, and in the other case, increased epidermal pigmentation as well as dermal melanocytosis were found. We suggested that the various treatment modalities of melasma should be applied depend on i...

AbstractIntroduction : Melasma is one of the most common hyperpigmentation disorders among womans, patches which commonly found on face especially sunlight exposured area. One factors causing melasma use oral contraceptives cause buildup hormones estrogen and progesterone skin.Objectives Thus, aim study to analyze association between duration contraceptive pills melasma.Methods This used a cros...

BACKGROUND Melasma is acquired symmetric hypermelanosis characterized by light-to-deep brown pigmentation over cheeks, forehead, upper lip, and nose. Treatment of this condition is difficult and associated with high recurrence rates. Chemical peels have become a popular modality in the treatment of melasma. OBJECTIVE To compare the therapeutic efficacy and tolerability of glycolic acid (35%) ...