Background: Mena is an immunofluorescence-based, quantitative method in which expression of the noninvasive Mena protein isoform (Mena11a) is subtracted from total Mena protein expression. Previous work has found a significant positive association between Mena and risk of death from breast cancer. Our goal was to determine if Mena could be used as an independent prognostic marker for axillary n...

The spread of cancer during metastatic disease requires that tumor cells subvert normal regulatory networks governing cell motility to invade surrounding tissues and migrate toward blood and lymphatic vessels. Enabled (Ena)/vasodilator-stimulated phosphoprotein (VASP) proteins regulate cell motility by controlling the geometry of assembling actin networks. Mena, an Ena/VASP protein, is upregula...

Noncommunicable diseases (NCDs) are a major and increasing global health issue. The World Health Organization (WHO) estimates that NCDs represent 63% of all global deaths of which 3.9 million are due to chronic respiratory diseases (CRDs) and Chronic Obstructive Pulmonary Disease (COPD) in particular. COPD is now the third most common cause of death globally; 90% of these deaths occur in Low an...

The cytoskeleton regulatory protein Mena is reportedly overexpressed in breast cancer; however, data regarding its expression level and clinical significance in gastric carcinoma (GC) is limited. The aim of the present study was to investigate Mena expression levels and prognostic significance in GC. Mena mRNA expression level was determined by reverse transcription-quantitative polymerase chai...

This paper analyzes the impacts of financial liberalization and foreign bank entry on competitiveness and soundness of domestic banking system as well as credit growth in association with financial sector development, focusing on MENA region’s comparative benchmarking performances with those of middle -income countries. We find that financial sector development is positively related to foreign ...

Mena (mammalian Ena) is an actin regulatory protein involved in cell motility and adhesion. Based on its potential role in malignant transformation revealed in other organs, we analyzed the Mena expression in normal salivary glands (SG) and salivary tumors. Mena expression was determined in normal SG (n=10) and also benign (n=20) and malignant (n=35) lesions of SG. For the immunohistochemical s...

BACKGROUND The epidemiology of Chikungunya virus (CHIKV) in the Middle East and North Africa (MENA) is not well characterized despite increasing recognition of its expanding infection and disease burden in recent years. METHODOLOGY / PRINCIPAL FINDINGS Following Cochrane Collaboration guidelines and reporting our findings following PRISMA guidelines, we systematically reviewed records describ...

T his paper is to study the convergence of per capita income. Convergence clubs hypothesis is one of the forms of convergence hypotheses, implying that countries with the same initial level of economic development, technology, and government policies, tend to be similar in per capita income and thus have a tendency to cluster around a small number of poles. In order to test the hypot...

We investigate the effects of low oil prices and heightened geopolitical risks on economic growth investment in Middle East North Africa (MENA) countries. find that negative shocks to positive risk have adverse GDP investment. Moreover, we impact MENA countries is muted when are and/or level high. These findings cast doubts prospects mega-project transformation plans as envisioned 2030 visions ...