Loss of fitness due to the accumulation of deleterious mutations appears to be inevitable in small, obligately asexual populations, as these are incapable of reconstituting highly fit genotypes by recombination or back mutation. The cumulative buildup of such mutations is expected to lead to an eventual reduction in population size, and this facilitates the chance accumulation of future mutatio...

This paper introduces accumulation into list homomorphisms for systematic development of both efficient and correct parallel programs. New parallelizable recursive pattern called H-homomorphism is given, and transformations from sequential patterns in the H-form and Hform into (H-)homomorphism are shown. We illustrate the power of our formalization by developing a novel and general parallel pro...

Social networks of 35 mentally ill persons were studied in Lao villages. Mental illness was associated with a decrease in size of social networks, disproportionate reliance on family, and asymmetric instrumental exchange. Nonkin "sponsors" provided assistance to those alienated from or abandoned by relatives. For those with late onset or episodic course, past accumulation of "social reserve" or...

Why should we focus on the early years? One reason is the accumulation of evidence that indicates that the child's experience in the early years has profound consequences for later life. There are now many studies that present a consistent picture indicating that adversity in early life, such as frequently accompanies child poverty, is linked to: poor adult mental and physical health , adult mo...

Mosaic techniques have been used to obtain images with a large field of view from video sequences by assembling individual overlapping images. In existing methods of mosaic construction only consecutive frames are aligned. Accumulation of small alignment errors occur, and in the case of the image path returning to a previous position in the mosaic (looping path), a significant mismatch between ...

Analytical tools in business management are understood as a combination of information technologies and quantitative methods used to assist stakeholders to make better decisions. The contemporary business environment is dramatically changing by the massive accumulation of data. Now, as never before, the use of analytical tools must be expanded to take advantage of this growing digital universe....

New models for evolutionary processes of mutation accumulation allow hypotheses about the age-specificity of mutational effects to be translated into predictions of heterogeneous population hazard functions. We apply these models to questions in the biodemography of longevity, including proposed explanations of Gompertz hazards and mortality plateaus.

This paper examines the optimal (first-best) tax policy in a stochastic representative agent model that exhibits a “keeping up with the Joneses” utility function and imperfectly competitive product markets. We show that the optimal labor tax is a constant, whose sign is determined by the relative strength of consumption externality and monopoly power. Moreover, the optimal capital tax is unambi...

bstract. We present a modification of the new edge-directed inerpolation method that eliminates the prediction error accumulation roblem by adopting a modified training window structure, and exending the covariance matching into multiple directions to suppress he covariance mismatch problem. Simulation results show that the roposed method achieves remarkable subjective performance in reserving ...

The purpose of this article is to provide students and researchers entering the field of aging studies with an introduction to the evolutionary theories of aging, as well as to orient them in the abundant modern scientific literature on evolutionary gerontology. The following three major evolutionary theories of aging are discussed: 1) the theory of programmed death suggested by August Weismann...