Objectives The aim was to identify theoretically expected as well as actually reported benefits from drug development and the importance of individual patient benefits compared to the collective benefits to society in general. Background Ethical guidelines require that clinical research involving humans offer the potential for benefit. A number of characteristics can be applied to define rese...

A 38-year-old tuberculous male Pakistani presented with halitosis and a cough especially marked when lying on his left side. Barium swallow demonstrated a fistula between oesophagus and left main bronchus. Anti-tuberculous therapy and repeated cauterization failed to close the fistula. Thoracotomy confirmed a congenital oesophago-bronchial fistula. Division and suture resulted in cure.

We report on a 65-year-old female who complained of recurrent bronchopulmonary infections since 1999. She suffered from permanent cough and progressive dyspnea. The diagnosis of amyloidosis was made by bronchoscopic tissue biopsies, during which severe bleeding occurred. Argon-plasma-laser treatment stopped the bleeding and resulted in a successful recanalization of the left main bronchus. The ...

Foreign body (FB) aspiration is commonly seen in children and less commonly in the elderly. However, due to some social and cultural factors, a distinct group of tracheobronchial FB aspiration is increasingly recognized. We sought to assess our experience with such entity. A retrospective review of all cases with veil pin tracheobronchial FB aspiration in a single center over a 13-year period w...

Dharmakīrti （c. A.D. 600-660） mentioned two examples of esoteric literature in his Pramāṇavārttikasvavṛtti: the Ḍākinītantra and Bhaginītantra. Karṇakagomin 9-10th century） rephrased Bhaginītantra as Caturbhaginītantra （The Tantra Four Sisters） commentary on Pramāṇavārttikasvavṛtti titled Pramāṇavārttikaṭīkā. An earlier study presumed that Sisters here were four goddesses Jayā, Vijayā, Ajitā/Ja...