OBJECTIVE The present study examines whether or not baseline and acetazolamide (ACZ) Tc-99m MAG3 renography can assess renal blood flow reserve. METHODS Renography proceeded for 50 min after sequential injections of 370 MBq Tc-99m MAG3 for baseline renography and 10 min after a 1,000 mg injection of ACZ for ACZ renography. Effective renal plasma flow of renal cortex (cERPF) in each kidney and...

Objective: Glomerular filtration can eliminate a substance only from the filtered fraction of the renal plasma flow. Since that fraction normally is 20%, ERPF agents clear from the kidneys about five times as fast as GFR agents. In most chronic renal diseases, the filtration fraction (GFR divided by ERPF) is largely unaffected, so the GFR can be estimated by dividing the ERPF by five. The aim o...

We compared single-sample methods, proposed by Russell et al. and Bubeck et al., and camera-based methods in calculating 99mTc-MAG3 clearance, and determined camera-based methods that provide estimates comparable to those measured by the Russell method. Twenty-one patients underwent 99mTc-MAG3 renal scintigraphy, and clearance was measured by the Russell method and Bubeck method. Various renogr...

Background 99mTc-mercaptoacetyl-triglycine (99mTc-MAG3) has been used for dynamic renal imaging since about 30 years. Free pertechnetate (99mTcO4), colloidal 99mTc ((99mTcO2)n), 99mTc-tartrate (precursor), precomplexes (99mTc-(MAG3)x) and lipophilic 99mTc-MAG2 are the main radiochemical impurities that may occur in the preparation. The total amount of these impurities has to be identified befor...

Received 9/26/2000; accepted 10/24/2000. For correspondence or reprints contact: Theodore S.T. Wang, Ph.D., Department of Radiology, College of Physicians and Surgeons, Columbia University, 622, West 168 Street, New York, NY 10032, U.S.A. Tel: (212)-3056466, Fax: (212)-3052962, E-mail: [email protected] Backgrounds: Following coronary angioplasty restenosis occurs in ≥30% of cases. Local irradi...

The Sandaozhuang super-large W-Mo deposit is located in the southern margin of North China Craton, within well-known East Qinling Mo mineralization belt, and one typical skarn-type deposits China. Based on EMPA LA-ICP-MS analyses, major trace elements were presented, mineral chemistry magnetite at various stages was discussed. Combining field observations, petrography, geochemical characteristi...

Recent studies have suggested that technetium-99m (19mTc) MAG3 can be substituted for iodine-131 ( 131 I) OIH, with better image quality and lower radiation dose. This study compares the two radiopharmaceuticals for effective renal plasma flow (ERPF) results using only the camera method. Twenty patients with varying degrees of renal impairment were studied. In 13 of these patients, direct compa...

Recent studies have suggested that technetium-99m (19mTc) MAG3 can be substituted for iodine-131 ( 131 I) OIH, with better image quality and lower radiation dose. This study compares the two radiopharmaceuticals for effective renal plasma flow (ERPF) results using only the camera method. Twenty patients with varying degrees of renal impairment were studied. In 13 of these patients, direct compa...

Mercaptoacetyltriglycine forms complexes with (186/188)Re and (99m)Tc radionuclides that are useful in nuclear medicine because they are substrates of the renal anion transport system. However, the renal clearance of [MO(MAG(3))](2-)(MAG(3) = penta-anionic form of mercaptoacetyltriglycine, M = Re, Tc) complexes are less than ideal. Organic sulphonates are also transported by the renal anion tra...

Nuclear Renogram can play an invaluable role in assessment of post renal transplant complication. Early recognition of renal functions loss after renal transplant can allow early management of high probability of salvaging the renal function. Subsequently an urgent USG KUB & doppler of transplant kidney was performed which revealed absent perfusion in upper half of transplant with finding sugge...