Electrical current at physiological strength has been applied as a therapeutic approach for various diseases. Several of our works showed that mild electrical stimulation (MES) at 0.1-ms pulse width has positive impact on organisms. But despite the growing evidence of the beneficial effects of MES, its effects on individual animals and the molecular underpinnings are poorly understood and rarel...

The present study was undertaken to determine the main metabolic secretory signals generated by the mitochondrial substrate MeS (methyl succinate) compared with glucose in mouse and rat islets and to understand the differences. Glycolysis and mitochondrial metabolism both have key roles in the stimulation of insulin secretion by glucose. Both fuels elicited comparable oscillatory patterns of Ca...

BACKGROUND The metabolic syndrome (MeS) is a common risk factor for coronary heart disease (CHD) in the general population. OBJECTIVES We examined the association between MeS and its risk in terms of CHD in patients on hemodialysis (HD). PATIENTS AND METHODS This study was conducted on 300 patients on HD in six HD centers during March 2012. Patients were divided in two groups regarding pres...

Evidence of the association between 25-hydroxyvitamin D (25(OH)D) and metabolic syndrome (MeS) remains uncertain and incongruent. This study aimed to determine the association between 25(OH)D and MeS among Jordanian adults. A complex multistage sampling technique was used to select a national population-based household sample. The present report deals exclusively with adults aged > 18 years who...

Surface myoelectric signals (MES) can be used as effective input for the control of upper arm prostheses. The concept of myoelectric control was introduced in the 1940’s [1]. Initially, amplitude measures were used to parameterize the MES, but simple approach imposed a practical limit of a three state system for each MES control site (e.g. rest, hand open, and hand close) [2]; therefore, to imp...

This paper presents a concept of development of Manufacturing Execution System (MES) by using simulations. MES is one of manufacturing systems that are used to bridge the data between the gap of the bottom layer (such as the shop floor control) and the enterprise system layer (such as Enterprise Resource Planning: ERP). The paper focuses on the functions of MES which link the levels of operatio...

Activation of nuclear factor κB (NF-κB) induces mesenchymal (MES) transdifferentiation and radioresistance in glioma stem cells (GSCs), but molecular mechanisms for NF-κB activation in GSCs are currently unknown. Here, we report that mixed lineage kinase 4 (MLK4) is overexpressed in MES but not proneural (PN) GSCs. Silencing MLK4 suppresses self-renewal, motility, tumorigenesis, and radioresist...

teucrium polium (labiatae) is a plant that widely grows in iran. some of species of teucrium are used for a considerable range of actions in traditional medicine and t. polium has frequently been used as anticonvulsant. in this study, we investigated the protective effects of t. polium ethanolic aqueous extracts and related fractions on seizures induced by pentylenetetrazole (ptz) and maximal e...

The paper is focused mainly on ERP and MES integration and is structured in the following way. Firstly the background on ERP and MES Evolution is presented. Then, MES functionalities are analyzed and a modified functionality model is suggested. After that a pertinent issues of ERP and MES are treated. In the final section will be discussed decisive findings and future trends of MESs, which are ...

A new tripodal ligand that features three selenium donors, namely the tris(2-seleno-1-mesitylimidazolyl)hydroborato ligand, [Tse(Mes)], has been constructed via the reaction of KBH(4) with 1-mesitylimidazole-2-selone; comparison of the IR spectroscopic data of [Tse(Mes)]Re(CO)(3) with those of a variety of related LRe(CO)(3) complexes demonstrates that the [Tse(Mes)] ligand is more strongly ele...