Cell culture, tissue chemistry and flow cytometry were used to determine whether antisense c-Met oligodeoxynucleotides enhanced the sensitivity of human glioma cells to paclitaxel. A combination of paclitaxel with antisense c-Met oligodeoxynucleotides inhibited cell growth, induced apoptosis and induced c-Met protein expression in U251 and SHG44 human glioma cells more significantly than either...

BACKGROUND Previously, we identified a sequence variant (N375S) of c-Met gene, however, its association with lung cancer risk and prognosis remain undefined. PATIENTS AND METHODS We investigated the genotype distribution of the c-Met-N375S sequence variant in 206 lung cancer patients and 207 non-cancer controls in the Taiwanese population by DNA sequencing. RESULTS Lung cancer patients with...

ownloade kground: Estimates of human papillomavirus (HPV) concordance among sexual partners are imporr various public health activities, from counseling individual patients to predicting the effect of HPV ation. thods:We systematically searched the PubMed and EMBASE databases for studies of HPV concordance heterosexual couples published through 2008 in English. Two coders independently abstract...

Background and aims: Neurofeedback is a relatively new therapy focusing on the core symptoms of inattention, impulsivity and hyperactivity.We undertook a meta-analysis to estimate the effectiveness of neurofeedback on attention deficit disorder in Iran. Methods: International databases of Pubmed, Scopus, ISI, Google Scholar, and national databases of Sid, Med ...

background:herbal methionine can be compared relative todl-methionine with evaluation of bioavailability of this source ofmethionine. objectives: an experiment was carried out todetermine the relative bioefficacy of herbal methionine (h-met)®relative to dl-methionine (dl-met) on performance criteria andimmunocompetence of met sources in male broilers. atotal of 160male broilers were fed a met-d...

BACKGROUND c-Met has been recognized as an important therapeutic target in gastric cancer, but the prognostic property of the c-Met status is still unclear. We aimed to characterize the prognostic effect of c-Met by systematic review and meta-analysis. METHODS We identified 15 studies assessing survival in gastric cancer by c-Met status. Effect measure of interest was hazard ratio (HR) for su...