Attempts to recreate all the developmental stages of Trypanosoma cruzi in vitro have thus far been met with partial success. It is possible, for instance, to produce trypomastigotes in tissue culture and to obtain metacyclic trypomastigotes in axenic conditions. Even though T. cruzi amastigotes are known to differentiate from trypomastigotes and metacyclic trypomastigotes, it has only been poss...

This thesis is concerned with Hilbert functions of ideals of finite group orbits, focusing in particular on abelian and metacyclic groups. Conjecture 16 in Section 4 characterizes the Hilbert functions that arise from two-dimensional representations of certain abelian groups, and a proof of the necessity of its conditions is provided. In Section 6, Proposition 18 gives a bound for the Hilbert f...

Transmission of leishmaniasis is effected by a specific developmental stage, the metacyclic promastigote. The precursors of metacyclic promastigotes were a distinct subpopulation of parasites, identified for the first time as a new stage in the life-cycle and named leptomonad promastigotes. Microdissection of infected sandflies into 4 midgut regions and foregut allowed precursor-product relatio...

Metacyclic trypomastigotes ol the CL strain of Trypanosoma cruzi obtained from triatomid vectors and from axenic cultures were comparatively analysed as to their antigen make-up and immunogenic characteristics. They were found to be similar by the various parameters examined. Thus, sera of mice immunized with either one of the two metacyclic types precipitated a 82Kd surface protein from 1 3 1I...

Suppose that a finite group G admits a Frobenius group of automorphisms FH with kernel F and complement H such that the fixed-point subgroup of F is trivial: CG(F ) = 1. In this situation various properties of G are shown to be close to the corresponding properties of CG(H). By using Clifford’s theorem it is proved that the order |G| is bounded in terms of |H| and |CG(H)|, the rank of G is boun...

For any finite Galois field extension K/F, with group G = Gal (K/F), there exists an element $$\alpha \in $$ K whose orbit $$G\cdot\alpha$$ forms F-basis of K. Such an $$\alpha$$ is called a normal element, and a normal basis. We introduce probabilistic algorithm for testing whether given \in$$ K normal, when G is either abelian or metacyclic group. The is based on the fact that deciding ...

The life cycle of Leishmania parasites within the sand fly vector includes the development of extracellular promastigotes from a noninfective, procyclic stage into an infective, metacyclic stage that is uniquely adapted for transmission by the fly and survival in the vertebrate host. These adaptations were explored in the context of the structure and function of the abundant surface lipophospho...

The transformation of Trypanosoma cruzi epimastigotes to the mammal infective metacyclic trypomastigotes (metacyclogenesis) can be performed in vitro under chemically defined conditions. Under these conditions, differentiating epimastigotes adhere to a surface before their transformation into metacyclic trypomastigotes. Scanning and transmission electron microscopy of adhered and non-adhered pa...

We study a classM of cyclically presented groups that includes both finite and infinite groups and is defined by a certain combinatorial condition on the defining relations. This class includes many finite metacyclic generalized Fibonacci groups that have been previously identified in the literature. By analysing their shift extensions we show that the groups in the class M are are coherent, su...