نتایج جستجو برای: metaplastic carcinoma
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Metaplastic breast cancer characterized by the presence of non-epithelial cellular elements is rare: representing less than 1% of breast carcinomas of typically highly aggressive, heterogeneous, chemo-resistant malignant tumors [1]. Low grade adenosquamous carcinoma [LGASC] is a rare variant of metaplastic carcinoma that is also characterized as a subgroup of triple negative breast cancers. Ini...
Metaplastic breast carcinoma (MBC) is a rare heterogeneous malignancy, accounting for <1% of all invasive breast carcinomas, in which adenocarcinoma is found to coexist with an admixture of spindle, squamous, chondroid or bone-forming neoplastic cells. Melanocytic variant was first described by Ruffolo et al. in 1997. We report a case of MBC, melanocytic variant, in a 57-year-old Nigerian femal...
Tumor infiltrating lymphocytes (TILs) were evaluated in many cancers like ovarian tumors, endometrial colon cancer and melanoma. Now there is increasing trend evaluating TILs breast cancer. gives the patients immune response to tumor. 100 cases of Modified radical mastectomy specimen chosen from surgical pathology records. The representative formalin fixed paraffin embedded tissue samples colle...
Apocrine carcinoma, which is strictly defined as over 90% of tumor cells showing apocrine differentiation, is a rare variant of breast cancer. Here we report an uncommon case in which apocrine carcinomas developed concurrently in both breasts; in addition, a sarcomatoid spindle cell lesion was coincident in the right breast. Both apocrine carcinomas were immunohistochemically negative for estro...
Introduction: Gastric carcinogenesis frequently affects tumor suppressor TP53 gene, resulting in increased expression of p53 protein and mutations towards later stages Carcinoma. Objectives: To analyze different gastric cancer to determine if it could be used as a biomarker allow targeted screening high risk groups with intestinal metaplasia. Methods: We retrieved 101 formalin fixed paraffin em...
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