The aim of this study was to establish a metastatic human neuroblastoma (NB) mouse model by xenograft in order to study the metastatic mechanisms of NB. A human NB cell line was obtained from a 5-year-old patient and cultured in vitro. A suspension of these cells was subcutaneously inoculated into nude mice at the right flank next to the forelimb. The biological characteristics of the developed...

metastatic tumors to the heart unlike primary cardiac tumors are not rare. despite its frequency, cardiac metastasis is commonly detected only during autopsy as the symptoms of disseminated metastasis prevail over symptoms caused by cardiac metastasis and hence is overlooked most of the time. tumors more commonly found metastasizing to the heart are malignancies of lung, breast, esophagus, lymp...

aim : to create an orthotopic hepatoma model with local metastasis monitored with ultrasound could be created as a platform for testing new treatments.   background : hepatoma accounts for 25% of liver tumors in children with poor overall survival. intraabdominal metastasis are present in 35% of patients at time of diagnosis.  we hypothesized that an orthotopic tumor model with local metastasis...

Genitourinary and colon tumors which constitutes frequent sources to metastatic tumors of the penis, are relatively more common tumors in the society. Though its rich vascularization, metastatic tumor of the penis is very rare. This can be considered to be a gladsome situation in terms of hopeless survey of metastatic penile tumors. The main goal of treatment is to improve the comfort and quali...

background: tumors involving the hand skeleton are rare. however, a basic knowledge of hand tumors is necessary for every clinician. this is due to the importance of distinguishing typical benign tumors from life or limb threatening malignant ones. methods: this study is a review of 99 cases of osseous hand tumors presented to the department of orthopedic surgery, imam khomeini hospital in tehr...

the majority of osseous tumors of the hand are benign. the surgeon who evaluates and treats osseous tumors of the hand has to be familiar with limb anatomy, tumor biology, various presentations of the tumors and the range of treatment possibilities and their limitations. lesions in the hand more often present earlier in their course than those at other sites, just because they are more likely t...