Methicillin-resistant Staphylococcus aureus (MRSA) is one of the most important multidrug-resistant pathogens around the world. MRSA is generated when methicillin-susceptible S. aureus (MSSA) exogenously acquires a methicillin resistance gene, mecA, carried by a mobile genetic element, staphylococcal cassette chromosome mec (SCCmec), which is speculated to be transmissible across staphylococcal...

introduction: methicillin-resistant staphylococcus aureus (mrsa) is responsible for an increasing number of serious hospital- and community-acquired infections. usa300 is known to be the most common cause of community-acquired infections, but recently there have been some reports on hospital-acquired infections caused by this strain. methods: totally 171 isolates of s. aureus were collected fro...

Treatment of infections caused by Staphylococcus aureus is often confounded by the bacterium's ability to develop resistance to chemotherapeutic agents. Methicillin-resistant S. aureus (MRSA) arises through the acquisition of staphylococcal chromosomal cassette mec (SCCmec), a genomic island containing the methicillin resistance determinant, mecA. In contrast, resistance to vancomycin can resul...

OBJECTIVES A recently identified mecA homologue, mecC, in methicillin-resistant Staphylococcus aureus (MRSA) has been isolated from humans and different animal hosts. The aim of this study was to determine antimicrobial resistance and provide molecular characterization of MRSA and methicillin-resistant non-Staphylococcus aureus staphylococci (MRnSA) isolated from wildlife that carried the gene ...

background and objective: methicillin resistance in staphylococcus aureus is an increasingly important clinical problem. a chromosomal gene, meca, mediates resistance to penicillinase-resistant penicillins such as methicillin and oxacillin in staphylococcus aureus. we evaluated the validity of disk diffusion test by using oxacillin, methicillin and cefoxitin disks with consideration of the pres...

conclusions the present study showed a high prevalence of aminoglycoside-resistance genes among mrsa isolates in two cities in iran. results the results of drug susceptibility testing showed that the highest rate of resistance was against erythromycin in tehran (84.4%) and gentamicin (71.7%) in sari. all isolates were sensitive to vancomycin, and all strains harbored the meca gene. the aac (6’)...

Staphylococcus epidermidis is the most prevalent coagulase-negative Staphylococcus (CNS) and is a major cause of hospital bacteremia. Based on 18 reference strains and 149 Staphylococcus clinical strains, used in a novel multiplex PCR method, the aim of this study was to identify S. epidermidis with respect to the sequence of three genes: recN, which encodes a recombination/repair protein, mecA...

conclusions results of the present study showed that the tst and sea genes had high frequencies among the mrsa isolates. the increased prevalence of mrsa isolates containing different virulence genes, probably accompanied by antimicrobial resistance, can complicate the therapy of mrsa isolates. results all the tested isolates were susceptible to vancomycin, but resistant to penicillin (100%), e...

INTRODUCTION The characteristics and antimicrobial resistance profiles of Staphylococcus aureus differs according to geographical regions and in relation to antibiotic usage. The aim of this study was to determine the biochemical characteristics of the prevalent S. aureus from Ekiti State, Nigeria, and to evaluate three commonly used disk diffusion methods (cefoxitin, oxacillin, and methicillin...