MFM (myofibrillar myopathies) are caused by mutations in several sarcomeric components, including the Z-disc protein myotilin. The morphological changes typical of MFM include Z-disc alterations and aggregation of dense filamentous sarcomeric material. The causes and mechanisms of protein aggregation in myotilinopathies and other forms of MFM remain unknown, although impaired degradation may ex...

The task of the calculation of the dipole-dipole interaction between cobalt nanodot and magnetic tip was formalized and the computing algorithm was implemented in parallel C++ code with using of the MPI standard. The parallelization is fulfilled by means of the dividing total cycle and the passing the part of cycle in one process. Our parallel program allows obtain MagneticForce-Microscopy (MFM...

Separation of topographic features from magnetic images has been an issue for the past two decades in magnetic force microscopy (MFM). The frequent pickups of the topographic features are interpreted as transitions of the tip between bistable states of the tip-sample assembly in the noncontact and tapping regions. MFM using electrostatic force modulation demonstrates the separation of the topog...

In this work, the use of magnetic force microscopy (MFM) to acquire images of magnetic nanostructures in liquid environments is presented. Optimization of the MFM signal acquisition in liquid media is performed and it is applied to characterize the magnetic signal of magnetite nanoparticles. The ability for detecting magnetic nanostructures along with the well-known capabilities of atomic force...

Magnetic force microscopy (MFM) is a widely used technique for magnetic imaging. Besides its advantages such as the high spatial resolution and the easy use in the characterization of relevant applied materials, the main handicaps of the technique are the lack of control over the tip stray field and poor lateral resolution when working under standard conditions. In this work, we present a conve...

High resolution magnetic force microscopy (MFM) has been carried out on L1(0)-FePt dot arrays patterned by plasma modified nanosphere lithography. An ex situ tip magnetization reversal experiment is carried out to determine the magnetic domains and verify the imaging stability of MFM and the mutual perturbations between the magnetic tip and the sample. We have identified that the critical size ...

AIM To assess changes in motor function in patients with Duchenne muscular dystrophy using the Motor Function Measure (MFM). METHOD Three studies were performed. Two studies included only physiotherapy-treated patients, with 13 patients (males mean age 11y 7mo, SD 1y 10mo, range 8-14y) in the 3-month study and 41 patients (males mean age 14y 1mo, SD 5y 5mo, range 6-32y) in the 1-year study. A...

The current study reports the first family with confirmed myofibrillar myopathy MFM in the Middle East and the third family worldwide. This study highlights the importance of considering MFM in young patients presenting with idiopathic cardiomyopathy, arrhythmia or atrioventricular block in the Gulf states. This is the first report that presented 2 different types of cardiomyopathy and 2 differ...

Orientation adaptation and perceptual learning change orientation tuning curves of V1 cells. Adaptation shifts tuning curve peaks away from the adapted orientation, reduces tuning curve slopes near the adapted orientation, and increases the responses on the far flank of tuning curves. Learning an orientation discrimination task increases tuning curve slopes near the trained orientation. These c...

OBJECTIVE The objective of this study was to evaluate the role of hospitalists and Maternal Fetal Medicine (MFM) subspecialists in obstetrical inpatient care. STUDY DESIGN This electronic survey study was offered to members of the American College of Obstetrics & Gynecology (ACOG; n = 1,039) and the Society for Maternal-Fetal Medicine (SMFM; n = 1,813). RESULTS Overall, 607 (21%) respondent...