نتایج جستجو برای: mice fetus development

تعداد نتایج: 1765588  

Journal: :iranian journal of basic medical sciences 0
leila etemad pharmaceutical research center, mashhad university of medical sciences, mashhad, iran afshar mohammad department of anatomy, birjand university of medical sciences, birjand, iran 3 medical toxicology research center, mashhad university of medical sciences, mashhad, iran amir hooshang mohammadpour pharmaceutical research center, mashhad university of medical sciences, mashhad, iran.departments of pharmacodynamics and toxicology, school of pharmacy, mashhad university of medical sciences, mashhad, iran nasser vahdati mashhadi departments of pharmacodynamics and toxicology, school of pharmacy, mashhad university of medical sciences, mashhad, iran seyed adel moallem pharmaceutical research center, mashhad university of medical sciences, mashhad, iran.medical toxicology research center, mashhad university of medical sciences, mashhad, iran 4 departments of pharmacodynamics and toxicology, school of pharmacy, mashhad university of medical sciences, mashhad, iran

objective(s): anti-epileptic drugs (aeds) have the potential to affect fetal development throughout pregnancy. considering the broad therapeutic indications of pregabalin (pgb), its potential teratogenic effects and the levels of homocysteine have been studied.   materials and methods: timed-pregnant mice received one of three doses of pgb (20, 40 or 80 mg/kg/day) or the vehicle control during ...

Journal: :Journal of Medical Genetics 1975

Journal: :Antimicrobial agents and chemotherapy 1992
S R Gogu B S Beckman K C Agrawal

The effects of zidovudine (AZT) on the fetus were investigated in pregnant mice by using parameters such as the number of fetuses, fetal size, and the fetal hepatic cell clonogenic assay. AZT caused dose-dependent toxicity to the fetus upon administration via drinking water to pregnant mice from days 1 to 13 of gestation. At the 0.5-mg/ml dose level, AZT caused a decrease in the number of fetus...

حیاتی رودباری, نسیم, شریف دینی, حوا, پریور, کاظم,

Of different types of bio-compatible nano‌particles, iron oxide nanoparticle has attracted attention for its applications especially in medicine and magnetic resonance imaging (MRI). We decided to study histological changes in testis and spermatogenesis in mature male mice that are affected by ironoxide nanoparticles (Fe2O3) during fetal period. In this study, the mice were divided into three e...

Journal: :Environmental Health Perspectives 1976
D W Nebert S S Thorgeirsson G H Lambert

The Ah locus in the mouse controls the induction of cytochrome P1-450 and at least eleven associated monooxygenase activities. These enzyme systems metabolically potentiate and detoxify drugs, environmental pollutants, and other foreign chemicals, as well as numerous endogenous substrates. For certain substrates, it is known that cytochrome P1-450 produces different reactive intermediates and p...

Afshar Mohammad Amir Hooshang Mohammadpour Leila Etemad Nasser Vahdati Mashhadi Seyed Adel Moallem,

  Objective(s): Anti-epileptic drugs (AEDs) have the potential to affect fetal development throughout pregnancy. Considering the broad therapeutic indications of pregabalin (PGB), its potential teratogenic effects and the levels of homocysteine have been studied.   Materials and Methods: Timed-pregnant mice received one of three doses of PGB (20, 40 or 80 mg/kg/day) or the vehicl...

2006
R. V. Anthony M. D. Fanning L. C. Richter

Many factors affect the rate of fetal growth and development in addition to overall fetal well-being. In eutherian mammals, the placenta serves as the primary mediator and modulator of those factors that ultimately determine development rate. The placenta accomplishes this task in the following ways: (a) by serving as the site of nutrient and waste transfer between the mother and fetus; (b) by ...

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