introduction: decidua as the nearest mother's tissue layer to the fetus which is in direct contact with the embryo has an important role in composing the appropriate microenvironment for protection of allogenic fetus from mother's immune response. in this study the effect of supernatant from culture of decidual cells on dendritic cells regarding the induction of t-cell allogenic proliferation r...

protective action of ficus carica leaf ethanolic extract (obtained by maceration) was evaluated in an animal model of hepatotoxicity induced by carbon tetrachloride (ccl4). male albino mice were divided into six groups. group i was normal control group; group ii received olive oil (ccl4 solvent), groups iii-vi received ccl4. after inducing hepatic damage, group iii served as control for ccl4; a...

background: the present study was carried out to investigate the possible protective effects of royal jelly (rj) on oxymetholone (oxm)-induced oxidative liver injuries in mice. methods: in total, 32 adult male nmri mice were divided into four groups of eight mice each. mice in groups 1 and 2 were orally administered 5 mg/kg/day oxm for 30 days. at the same time, mice in group 3 received rj at a...

background and objectives: acrylamide is a monomer which is formed in foodstuffs containing carbohydrates altered to asparagine during thermal processing. vitamin e is a component in human diet considered as the most effective lipid-soluble antioxidant found in the biological system. it prevents initiation of oxidative tissue damage. the aim of this study was to investigate the potential role o...

The distribution of 14C after the administration of 14C-formaldehyde was studied in pregnant mice by a whole body low temperature autoradiographic technique. The concentrations of formaldehyde and its metabolites in maternal and fetal blood and tissues were determined in unsectioned tissues by liquid scintillation spectrophotometry. The binding of 14C from 14C-formaldehyde to cells and DNA in m...

Anthocyanins from Lycium ruthenicum Murry (LRAs) were used to explore the anti-fatigue activities of LRAs at different concentrations in a mouse fatigue model. Eight biochemical indexes determined liver tissue, muscle tissue and serum. The results showed that experiment mainly contained delphinium, petunidin malvidin. During 21 days gavage, there was no significant difference body weight. exerc...

severe hepatic failure accounts for many deaths and raises medical costs each year worldwide. currently, liver transplantation is the most common therapeutic option for patients with end-stage chronic liver disease. due to decrease in the number of organ donors, many in need of transplantation continue to remain on the waiting list. hepatic tissue engineering is a step toward alleviating the ne...

BACKGROUND Pregnancy induces adaptations in maternal metabolism to meet the increased need for nutrients by the placenta and fetus. Creatine is an important intracellular metabolite obtained from the diet and also synthesised endogenously. Experimental evidence suggests that the fetus relies on a maternal supply of creatine for much of gestation. However, the impact of pregnancy on maternal cre...