We introduce and analyze a model for osmotically spreading bacterial colonies at solid-air interfaces that includes wetting phenomena, i.e., surface forces. The model is based on a hydrodynamic description for liquid suspensions which is supplemented by bioactive processes. We show that surface forces determine whether a biofilm can expand laterally over a substrate and provide experimental evi...

Microbes, while living in close proximity in biofilms, may in other cases not be closely localized in the environment. In the latter case, their interactions and communications are dependent on myriad factors such as existence of direct connections (e.g., web of hyphae from fungi) or pools of water where they could migrate. Hence, disparate groups of microbes could subsist on nutrients in their...

A bio-inert surface chemistry was developed that can confine biofilm formation in designed patterns for at least 26 days.

GORDON, HELMUT A., AND EDITH BRUCKNER-KARDOSS. Efect of normal microbial flora on intestinal surface area. Am. J. Physiol. 201 (I) : I 75-178. I g6 I .-The mucosal surface area of the small intestine was determined in young adult, germfree and conventional rats. On the average, the germfree values were found to be 307~ lower than those of conventional animals. This reduction was pronounced in t...

BACKGROUND Microbial cellulose conversion by Clostridium thermocellum 27405 occurs predominantly through the activity of substrate-adherent bacteria organized in thin, primarily single cell-layered biofilms. The importance of cellulosic surface exposure to microbial hydrolysis has received little attention despite its implied impact on conversion kinetics. RESULTS We showed the spatial hetero...

GORDON, HELMUT A., AND EDITH BRUCKNER-KARDOSS. Efect of normal microbial flora on intestinal surface area. Am. J. Physiol. 201 (I) : I 75-178. I g6 I .-The mucosal surface area of the small intestine was determined in young adult, germfree and conventional rats. On the average, the germfree values were found to be 307~ lower than those of conventional animals. This reduction was pronounced in t...

Project Goals: The identification of microorganisms responsible for specific processes remains a major challenge in microbial ecology, one that requires the integration of multiple techniques. We propose to address this goal by developing a new methodology, “Chip-SIP”; combining the power of re-designed oligonucleotide microarrays with nano-scale secondary ion mass spectrometry (NanoSIMS) analy...