BACKGROUND Urinary tract infection (UTI) is a common infection in primary care and is the second leading reason for prescription of antibiotics in Denmark. The diagnosis is often based on symptoms and urine dip-stick, which has limited validity, causing the risk of unnecessary antibiotic prescription. Additionally, with increasing antibiotic resistance, the risk of choosing an antibiotic to whi...

25 Stenotrophomonas maltophilia is a multi-drug resistant organism increasingly isolated from the 26 lungs of cystic fibrosis (CF) patients. One hundred twenty-five S. maltophilia isolates from 85 27 CF patients underwent planktonic and biofilm susceptibility testing against 9 different 28 antibiotics, alone and in double antibiotics combinations. When S. maltophilia were grown as a 29 biofilm,...

Antimicrobial susceptibility testing is essential for guiding the treatment of many types of bacterial infections, especially in the current context of rising rates of antibiotic resistance. The most commonly employed methods rely on the detection of phenotypic resistance by measuring bacterial growth in the presence of the antibiotic being tested. Although these methods are highly sensitive fo...

The purpose of this study was to determine the prevalence of anti-microbial resistance in intubated patients in intensive care unit (ICU) of Bahonar hospital in Kerman province, Iran during the year 2008. Tracheal samples were obtained from 111 intubated patients in the ICU by broncoalveolar lavage method. Amikacin, Ceftazidim and Imipenem were used to evaluate antibiotic susceptibility. For ...

the purpose of this study was to determine the prevalence of anti-microbial resistance in intubated patients in intensive care unit (icu) of bahonar hospital in kerman province, iran during the year 2008. tracheal samples were obtained from 111 intubated patients in the icu by broncoalveolar lavage method. amikacin, ceftazidim and imipenem were used to evaluate antibiotic susceptibility. for de...

We performed bedaquiline broth microdilution susceptibility testing using Clinical and Laboratory Standards Institute (CLSI) guidelines on 103 respiratory isolates of Mycobacterium avium complex (MAC), including multidrug-resistant isolates. Approximately 90% of isolates had bedaquiline MICs of ≤0.008 μg/ml, and 102/103 isolates had MICs of ≤0.015 μg/ml. Bedaquiline has excellent potential for ...

Due to a recent resurgence in tuberculosis research focused on drug development, several new antituberculosis drugs are in the pipeline, and the standard of care for tuberculosis might soon change. If new drugs replace the current first-line treatment, then existing classifications of resistance, including multidrug-resistant and extensively drug-resistant tuberculosis, might become less releva...

The monthly variation in geometric mean MICs (GMICs) of amikacin, tobramycin, and gentamicin for Escherichia coli and Pseudomonas aeruginosa laboratory controls and clinical isolates was followed for 30 months. For 19 months, MICs were determined by using Micro-Media system (MMS; Micro-Media Systems, Inc., Potomac, Md.) microdilution panels, and for the other 11 months, MicroScan (MS; American ...

OBJECTIVES Rates of macrolide resistance in group A streptococci (GAS) were reported to be low in the US in the 1990s. However, we documented an unexpectedly high rate of macrolide resistance among GAS in Pittsburgh, PA, in 2001 and 2002. In an effort to define the current prevalence of macrolide-resistant GAS in the US, a multicentre surveillance project was initiated. METHODS Between Octobe...