background: angiogenesis, the development of new blood vessels, is an important process in tissue development and wound healing, but becomes pathologic when associated with solid tumor growth, proliferative retinopathies, and rheumatoid arthritis. accurate and reliable qualification of neovascular (angiogenic) response, both in vitro and in vivo, is an essential requirement for the study of new...

Conventional washing and sanitizing approaches for leafy greens provide limited inactivation of bacteria on leaf surfaces. For a quantitative understanding the barriers to bacterial surfaces, this study develops numerical simulation approach based mass transport surface reaction kinetics. Two specific sections surface, i.e., local region with “macroscale” veins “microscale” contours without vei...

Cartilage Tissue Engineering In article number 2212114, Wenguo Cui, Qi Gu, Ming-Zhu Zhang, and co-workers introduce novel cartilage lacuna-inspired microcarriers with geometric constraints to repress chondrocyte dedifferentiation by inhibiting Wnt signaling. The biomimetic display favorable cytocompatibility drive robust hyaline chondrocyte-derived neocartilage formation. This study paves the w...

A microfluidic approach to a honeycomb-structure material based on the synergistic effects of polymer rapid precipitation, double emulsion templating, and internal effervescent salt decomposition is reported. The delicate honeycomb structure exhibits unique characteristics with an external nanopore membrane and internal multiple cavities. The biological functionality of the artificial structure...

This article presents a one-step method for generating complex emulsions that exploits the phase separation of the emulsion droplet generated in the microchannel. This approach easily produces double, triple, quadruple, and Janus emulsions with monodisperse size. These emulsions can be used as useful templates for the synthesis of new functional materials, such as microcapsules, hemispheres, Ja...

Rapidly expanding skeletal muscle satellite cells with cost-effective methods have been presented as a solution for meeting the growing global demand meat. A common strategy scaling cell proliferation employs microcarriers, small beads designed to support anchorage-dependent in suspension-style bioreactors. No carrier has yet marketed cultivation of lab-grown The objective this study was demons...