This study focuses on the fabrication and characterization of Love wave surface acoustic wave (LW-SAW) sensors with a thin nano-crystalline diamond (NCD) coating with an integrated microfluidics system. The effect of diamond layer thickness on the acoustic wave phase velocity and the sensor’s sensitivity have been investigated experimentally and compared with theoretical simulations. The fabric...

Society deems largess in the affirmative; the more money the better; the larger the house the grander; the bigger the bicep the stronger. The world of scientific discovery, invention, and development is, on the contrary, moving counter to this belief. Need for high throughput methods requiring small quantities of material have prompted the design and development of instruments with novel platfo...

This paper describes development and experimental verifications of wireless powering for EWOD microfluidics. First, the wireless powering is achieved by planar PCB coils (not by bulky, spool-type, conventional coils), resulting in seamless integration with EWOD array electrodes on a single and compact chip. Second, the obtained voltage for wireless EWOD is over 230Vrms, much higher than typical...

Droplet-based microfluidic systems have been shown to be compatible with many chemical and biological reagents and capable of performing a variety of "digital fluidic" operations that can be rendered programmable and reconfigurable. This platform has dimensional scaling benefits that have enabled controlled and rapid mixing of fluids in the droplet reactors, resulting in decreased reaction time...

Digital microfluidics (DMF) is an emerging liquid-handling technology that enables individual control over droplets on an open array of electrodes. These picoliter- to microliter-sized droplets, each serving as an isolated vessel for chemical processes, can be made to move, merge, split, and dispense from reservoirs. Because of its unique advantages, including simple instrumentation, flexible d...

In recent years, origami/paper folding art has been applied to more and scientific research due the efficiently producing tiny structures at a low cost; inspired by this, origami microfluidics (the combination of with paper-based microfluidics) also proposed. microfluidic devices, three-dimensional fluid paths can be formed directly paper pre-deposited hydrophobic barriers accomplish complex ma...

Immunoassays have greatly benefited from miniaturization in microfluidic systems. This review, which summarizes developments in microfluidics-based immunoassays since 2000, includes four sections, focusing on the configurations of immunoassays that have been implemented in microfluidics, the main fluid handling modalities that have been used for microfluidic immunoassays, multiplexed immunoassa...

Microfluidic devices offer automation and high-throughput screening, and operate at low volumes of consumables. Although microfluidics has the potential to reduce turnaround times and costs for analytical devices, particularly in medical, veterinary, and environmental sciences, this enabling technology has had limited diffusion into consumer products. This article analyzes the microfluidics mar...

Droplet microfluidics is enabling reactions at nano- and picoliter scale, resulting in faster and cheaper biological and chemical analyses. However, varying concentrations of samples on a drop-to-drop basis is still a challenging task in droplet microfluidics, primarily limited due to lack of control over individual droplets. In this paper, we report an on-chip microfluidic droplet dilution str...

The field of microfluidics has seen breath-taking progress since its beginnings in the 1980s and early 1990s. While much of the initial work was a by-product of mainstream micro-electro-mechanical systems (MEMS) and silicon based fabrication schemes, soon a specialized research field developed. Over the last decade a strong, highly interdisciplinary microfluidics community emerged with roots in...